Sexual development and cryptic sexuality in fungi: insights from Aspergillus species - PubMed (original) (raw)
Review
Sexual development and cryptic sexuality in fungi: insights from Aspergillus species
Paul S Dyer et al. FEMS Microbiol Rev. 2012 Jan.
Free article
Abstract
Major insights into sexual development and cryptic sexuality within filamentous fungi have been gained from investigations using Aspergillus species. Here, an overview is first given into sexual morphogenesis in the aspergilli, describing the different types of sexual structures formed and how their production is influenced by a variety of environmental and nutritional factors. It is argued that the formation of cleistothecia and accessory tissues, such as Hülle cells and sclerotia, should be viewed as two independent but co-ordinated developmental pathways. Next, a comprehensive survey of over 75 genes associated with sexual reproduction in the aspergilli is presented, including genes relating to mating and the development of cleistothecia, sclerotia and ascospores. Most of these genes have been identified from studies involving the homothallic Aspergillus nidulans, but an increasing number of studies have now in addition characterized 'sex-related' genes from the heterothallic species Aspergillus fumigatus and Aspergillus flavus. A schematic developmental genetic network is proposed showing the inter-relatedness between these genes. Finally, the discovery of sexual reproduction in certain Aspergillus species that were formerly considered to be strictly asexual is reviewed, and the importance of these findings for cryptic sexuality in the aspergilli as a whole is discussed.
© 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.
Similar articles
- A fungal sexual revolution: Aspergillus and Penicillium show the way.
Dyer PS, O'Gorman CM. Dyer PS, et al. Curr Opin Microbiol. 2011 Dec;14(6):649-54. doi: 10.1016/j.mib.2011.10.001. Epub 2011 Oct 25. Curr Opin Microbiol. 2011. PMID: 22032932 Review. - Aspergillus: sex and recombination.
Varga J, Szigeti G, Baranyi N, Kocsubé S, O'Gorman CM, Dyer PS. Varga J, et al. Mycopathologia. 2014 Dec;178(5-6):349-62. doi: 10.1007/s11046-014-9795-8. Epub 2014 Aug 14. Mycopathologia. 2014. PMID: 25118872 Review. - Evolution of asexual and sexual reproduction in the aspergilli.
Ojeda-López M, Chen W, Eagle CE, Gutiérrez G, Jia WL, Swilaiman SS, Huang Z, Park HS, Yu JH, Cánovas D, Dyer PS. Ojeda-López M, et al. Stud Mycol. 2018 Sep;91:37-59. doi: 10.1016/j.simyco.2018.10.002. Epub 2018 Oct 11. Stud Mycol. 2018. PMID: 30425416 Free PMC article. - The gprA and gprB genes encode putative G protein-coupled receptors required for self-fertilization in Aspergillus nidulans.
Seo JA, Han KH, Yu JH. Seo JA, et al. Mol Microbiol. 2004 Sep;53(6):1611-23. doi: 10.1111/j.1365-2958.2004.04232.x. Mol Microbiol. 2004. PMID: 15341643 - Evidence for sexuality in the opportunistic fungal pathogen Aspergillus fumigatus.
Paoletti M, Rydholm C, Schwier EU, Anderson MJ, Szakacs G, Lutzoni F, Debeaupuis JP, Latgé JP, Denning DW, Dyer PS. Paoletti M, et al. Curr Biol. 2005 Jul 12;15(13):1242-8. doi: 10.1016/j.cub.2005.05.045. Curr Biol. 2005. PMID: 16005299
Cited by
- Evolution of Mating Systems in Basidiomycetes and the Genetic Architecture Underlying Mating-Type Determination in the Yeast Leucosporidium scottii.
Maia TM, Lopes ST, Almeida JM, Rosa LH, Sampaio JP, Gonçalves P, Coelho MA. Maia TM, et al. Genetics. 2015 Sep;201(1):75-89. doi: 10.1534/genetics.115.177717. Epub 2015 Jul 14. Genetics. 2015. PMID: 26178967 Free PMC article. - Aspergillus fumigatus and Aspergillosis in 2019.
Latgé JP, Chamilos G. Latgé JP, et al. Clin Microbiol Rev. 2019 Nov 13;33(1):e00140-18. doi: 10.1128/CMR.00140-18. Print 2019 Dec 18. Clin Microbiol Rev. 2019. PMID: 31722890 Free PMC article. Review. - Metabolism and Development during Conidial Germination in Response to a Carbon-Nitrogen-Rich Synthetic or a Natural Source of Nutrition in Neurospora crassa.
Wang Z, Miguel-Rojas C, Lopez-Giraldez F, Yarden O, Trail F, Townsend JP. Wang Z, et al. mBio. 2019 Mar 26;10(2):e00192-19. doi: 10.1128/mBio.00192-19. mBio. 2019. PMID: 30914504 Free PMC article. - Comparative genomics to explore phylogenetic relationship, cryptic sexual potential and host specificity of Rhynchosporium species on grasses.
Penselin D, Münsterkötter M, Kirsten S, Felder M, Taudien S, Platzer M, Ashelford K, Paskiewicz KH, Harrison RJ, Hughes DJ, Wolf T, Shelest E, Graap J, Hoffmann J, Wenzel C, Wöltje N, King KM, Fitt BD, Güldener U, Avrova A, Knogge W. Penselin D, et al. BMC Genomics. 2016 Nov 22;17(1):953. doi: 10.1186/s12864-016-3299-5. BMC Genomics. 2016. PMID: 27875982 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources