Next generation sequencing and bioinformatic bottlenecks: the current state of metagenomic data analysis - PubMed (original) (raw)

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Next generation sequencing and bioinformatic bottlenecks: the current state of metagenomic data analysis

Matthew B Scholz et al. Curr Opin Biotechnol. 2012 Feb.

Abstract

The recent technological advances in next generation sequencing have brought the field closer to the goal of reconstructing all genomes within a community by presenting high throughput sequencing at much lower costs. While these next-generation sequencing technologies have allowed a massive increase in available raw sequence data, there are a number of new informatics challenges and difficulties that must be addressed to improve the current state, and fulfill the promise of, metagenomics.

Copyright © 2011 Elsevier Ltd. All rights reserved.

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