The novel object recognition memory: neurobiology, test procedure, and its modifications - PubMed (original) (raw)

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The novel object recognition memory: neurobiology, test procedure, and its modifications

M Antunes et al. Cogn Process. 2012 May.

Abstract

Animal models of memory have been considered as the subject of many scientific publications at least since the beginning of the twentieth century. In humans, memory is often accessed through spoken or written language, while in animals, cognitive functions must be accessed through different kind of behaviors in many specific, experimental models of memory and learning. Among them, the novel object recognition test can be evaluated by the differences in the exploration time of novel and familiar objects. Its application is not limited to a field of research and enables that various issues can be studied, such as the memory and learning, the preference for novelty, the influence of different brain regions in the process of recognition, and even the study of different drugs and their effects. This paper describes the novel object recognition paradigms in animals, as a valuable measure of cognition. The purpose of this work was to review the neurobiology and methodological modifications of the test commonly used in behavioral pharmacology.

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References

    1. Aggleton JP, Albasser MM, Aggleton DJ, Poirier GL, Pearce JM. Lesions of the rat perirhinal cortex spare the acquisition of a complex configural visual discrimination yet impair object recognition. Behav Neurosci. 2010;124:55–68. doi: 10.1037/a0018320. - DOI - PMC - PubMed
    1. Albasser MM, Davies M, Futter JE, Aggleton JP. Magnitude of the object recognition deficit associated with perirhinal cortex damage in rats: effects of varying the lesion extent and the duration of the sample period. Behav Neurosci. 2009;123:115–124. doi: 10.1037/a0013829. - DOI - PubMed
    1. Aubele T, Kaufman R, Montalment F, Kritzer MF. Effects of gonadectomy and hormone replacement on a spontaneous novel object recognition task in adult male rats. Horm Behav. 2008;54:244–252. doi: 10.1016/j.yhbeh.2008.04.001. - DOI - PMC - PubMed
    1. Bahrick L, Hernandez-Reif M, Pickens J. The effect of retrieval cues on visual preferences and memory in infancy: evidence for a four-phase attention function. J Exp Child Psychol. 1997;67:1–20. doi: 10.1006/jecp.1997.2399. - DOI - PubMed
    1. Bahrick L, Gogate L, Ruiz I. Attention and memory for faces and actions in infancy: the salience of actions over faces in dynamic events. Child Dev. 2002;73:1629–1643. doi: 10.1111/1467-8624.00495. - DOI - PubMed

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