Purification to homogeneity of camel pituitary pro-opiocortin, the common precursor of opioid peptides and corticotropin - PubMed (original) (raw)

Purification to homogeneity of camel pituitary pro-opiocortin, the common precursor of opioid peptides and corticotropin

S Kimura et al. Proc Natl Acad Sci U S A. 1979 Apr.

Abstract

Pro-opiocortin was purified from camel pituitaries by procedures including high-performance liquid chromatography. The precursor relationship of the pure protein to the opioid peptides and to corticotropin was confirmed. Partial chemical analysis consisting of amino acid analysis and tryptic peptide mapping was carried out with the aid of sensitive fluorescence detection.

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