IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data - PubMed (original) (raw)

IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data

Dan Wang et al. Bioinformatics. 2012.

Abstract

The Illumina Infinium HumanMethylation450 BeadChip is a newly designed high-density microarray for quantifying the methylation level of over 450 000 CpG sites within human genome. Illumina Methylation Analyzer (IMA) is a computational package designed to automate the pipeline for exploratory analysis and summarization of site-level and region-level methylation changes in epigenetic studies utilizing the 450K DNA methylation microarray. The pipeline loads the data from Illumina platform and provides user-customized functions commonly required to perform exploratory methylation analysis for individual sites as well as annotated regions.

Availability: IMA is implemented in the R language and is freely available from http://www.rforge.net/IMA.

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IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data - PubMed (original) (raw)