Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins - PubMed (original) (raw)
. 1990 Nov 8;348(6297):137-43.
doi: 10.1038/348137a0.
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- PMID: 2234077
- DOI: 10.1038/348137a0
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Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins
P J Kang et al. Nature. 1990.
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Abstract
By analysis of a temperature-sensitive yeast mutant, a heat-shock protein in the matrix of mitochondria, mitochondrial hsp70 (Ssc1p), is found to be involved both in translocation of nuclear-encoded precursor proteins across the mitochondrial membranes and in (re)folding of imported proteins in the matrix.
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