Sodium chloride intake: is lower always better? - PubMed (original) (raw)
Sodium chloride intake: is lower always better?
Hiddo Lambers Heerspink et al. J Am Soc Nephrol. 2012 Jul.
Abstract
Current treatment of kidney disease is not completely satisfactory, particularly when initiated in the late stages of renal progression. There is an urgent need for additional interventions, especially reduction of salt intake, which is rather high in the Western world. In this commentary we provide a critical assessment of post hoc analyses of recent interventional and observational studies on the effect of salt intake on renal and cardiovascular outcomes. To evaluate the mechanisms and safety of reduced salt intake, studies specifically designed to assess salt intake as an endpoint are needed. This approach will have implications for health care policies and labeling of the salt content of purchased foods.
Similar articles
- Salt-sensitive hypertension: renal and cardiovascular implications.
Campese VM. Campese VM. Nutr Metab Cardiovasc Dis. 1999 Jun;9(3):143-56. Nutr Metab Cardiovasc Dis. 1999. PMID: 10464787 Review. No abstract available. - Salt intake in kidney disease--a missed therapeutic opportunity?
Lambers Heerspink HJ, Navis G, Ritz E. Lambers Heerspink HJ, et al. Nephrol Dial Transplant. 2012 Sep;27(9):3435-42. doi: 10.1093/ndt/gfs354. Nephrol Dial Transplant. 2012. PMID: 22942175 Review. - [Salt sensitive blood pressure and the renin-angiotensin system in hypertension].
Krekels MM, de Leeuw PW. Krekels MM, et al. Ned Tijdschr Geneeskd. 1997 Nov 22;141(47):2285-9. Ned Tijdschr Geneeskd. 1997. PMID: 9550812 Review. Dutch. - Effect of high salt intake on local renin-angiotensin system and ventricular dysfunction following myocardial infarction in rats.
de Resende MM, Mill JG. de Resende MM, et al. Clin Exp Pharmacol Physiol. 2007 Apr;34(4):274-9. doi: 10.1111/j.1440-1681.2007.04556.x. Clin Exp Pharmacol Physiol. 2007. PMID: 17324137 - Effects of dietary salt on intrarenal angiotensin system, NAD(P)H oxidase, COX-2, MCP-1 and PAI-1 expressions and NF-kappaB activity in salt-sensitive and -resistant rat kidneys.
Chandramohan G, Bai Y, Norris K, Rodriguez-Iturbe B, Vaziri ND. Chandramohan G, et al. Am J Nephrol. 2008;28(1):158-67. doi: 10.1159/000110021. Epub 2007 Oct 19. Am J Nephrol. 2008. PMID: 17951998
Cited by
- Salt sensitivity and hypertension.
Balafa O, Kalaitzidis RG. Balafa O, et al. J Hum Hypertens. 2021 Mar;35(3):184-192. doi: 10.1038/s41371-020-00407-1. Epub 2020 Aug 29. J Hum Hypertens. 2021. PMID: 32862203 Review. - Magnetic resonance-determined sodium removal from tissue stores in hemodialysis patients.
Dahlmann A, Dörfelt K, Eicher F, Linz P, Kopp C, Mössinger I, Horn S, Büschges-Seraphin B, Wabel P, Hammon M, Cavallaro A, Eckardt KU, Kotanko P, Levin NW, Johannes B, Uder M, Luft FC, Müller DN, Titze JM. Dahlmann A, et al. Kidney Int. 2015 Feb;87(2):434-41. doi: 10.1038/ki.2014.269. Epub 2014 Aug 6. Kidney Int. 2015. PMID: 25100048 Free PMC article. - Public health relevance of drug-nutrition interactions.
Péter S, Navis G, de Borst MH, von Schacky C, van Orten-Luiten ACB, Zhernakova A, Witkamp RF, Janse A, Weber P, Bakker SJL, Eggersdorfer M. Péter S, et al. Eur J Nutr. 2017 Aug;56(Suppl 2):23-36. doi: 10.1007/s00394-017-1510-3. Eur J Nutr. 2017. PMID: 28748481 Free PMC article. - Dietary Salt Restriction in Chronic Kidney Disease: A Meta-Analysis of Randomized Clinical Trials.
Garofalo C, Borrelli S, Provenzano M, De Stefano T, Vita C, Chiodini P, Minutolo R, De Nicola L, Conte G. Garofalo C, et al. Nutrients. 2018 Jun 6;10(6):732. doi: 10.3390/nu10060732. Nutrients. 2018. PMID: 29882800 Free PMC article. Review. - High salt diet impairs memory-related synaptic plasticity via increased oxidative stress and suppressed synaptic protein expression.
Ge Q, Wang Z, Wu Y, Huo Q, Qian Z, Tian Z, Ren W, Zhang X, Han J. Ge Q, et al. Mol Nutr Food Res. 2017 Oct;61(10):1700134. doi: 10.1002/mnfr.201700134. Epub 2017 Aug 15. Mol Nutr Food Res. 2017. PMID: 28654221 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical