Getting RNA and protein in phase - PubMed (original) (raw)
Review
. 2012 Jun 8;149(6):1188-91.
doi: 10.1016/j.cell.2012.05.022.
Affiliations
- PMID: 22682242
- DOI: 10.1016/j.cell.2012.05.022
Free article
Review
Getting RNA and protein in phase
Stephanie C Weber et al. Cell. 2012.
Free article
Abstract
Nonmembrane-bound organelles such as RNA granules behave like dynamic droplets, but the molecular details of their assembly are poorly understood. Several recent papers identify structural features that drive granule assembly, shedding light on how phase transitions functionally organize the cell and may lead to pathological protein aggregation.
Copyright © 2012 Elsevier Inc. All rights reserved.
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