STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast - PubMed (original) (raw)

Comparative Study

. 1990 Nov;4(11):1862-74.

doi: 10.1101/gad.4.11.1862.

Affiliations

• PMID: 2276621
• DOI: 10.1101/gad.4.11.1862

Free article

Comparative Study

STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast

N Rhodes et al. Genes Dev. 1990 Nov.

Free article

Abstract

The STE11 gene of Saccharomyces cerevisiae is one of several genes required for mating between two haploid cell types of this yeast. Its product is required for response to a signal that causes arrest of the mitotic cell cycle in the G1 phase and induction of mating-type-specific genes. The nucleotide sequence of the STE11 gene was determined. The predicted amino acid sequence shows homology to the protein kinase family. We demonstrate that the STE11 product has kinase catalytic activity and that this activity is required for its in vivo functions.

PubMed Disclaimer

Similar articles

• Functional conservation between Schizosaccharomyces pombe ste8 and Saccharomyces cerevisiae STE11 protein kinases in yeast signal transduction.
  Styrkársdóttir U, Egel R, Nielsen O. Styrkársdóttir U, et al. Mol Gen Genet. 1992 Oct;235(1):122-30. doi: 10.1007/BF00286189. Mol Gen Genet. 1992. PMID: 1435723
• A dominant truncation allele identifies a gene, STE20, that encodes a putative protein kinase necessary for mating in Saccharomyces cerevisiae.
  Ramer SW, Davis RW. Ramer SW, et al. Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):452-6. doi: 10.1073/pnas.90.2.452. Proc Natl Acad Sci U S A. 1993. PMID: 8421676 Free PMC article.
• Genetically identified protein kinases in yeast. I: Transcription, translation, transport and mating.
  Hoekstra MF, Demaggio AJ, Dhillon N. Hoekstra MF, et al. Trends Genet. 1991 Aug;7(8):256-61. doi: 10.1016/0168-9525(91)90325-K. Trends Genet. 1991. PMID: 1771673 Review.
• Signal transduction in the budding yeast Saccharomyces cerevisiae.
  Oehlen B, Cross FR. Oehlen B, et al. Curr Opin Cell Biol. 1994 Dec;6(6):836-41. doi: 10.1016/0955-0674(94)90053-1. Curr Opin Cell Biol. 1994. PMID: 7880530 Review.

Cited by

• Sphingolipids regulate the yeast high-osmolarity glycerol response pathway.
  Tanigawa M, Kihara A, Terashima M, Takahara T, Maeda T. Tanigawa M, et al. Mol Cell Biol. 2012 Jul;32(14):2861-70. doi: 10.1128/MCB.06111-11. Epub 2012 May 14. Mol Cell Biol. 2012. PMID: 22586268 Free PMC article.
• MAP kinase pathways: the first twenty years.
  Avruch J. Avruch J. Biochim Biophys Acta. 2007 Aug;1773(8):1150-60. doi: 10.1016/j.bbamcr.2006.11.006. Epub 2006 Nov 15. Biochim Biophys Acta. 2007. PMID: 17229475 Free PMC article. Review.
• The phosphatase Ppt1 is a dedicated regulator of the molecular chaperone Hsp90.
  Wandinger SK, Suhre MH, Wegele H, Buchner J. Wandinger SK, et al. EMBO J. 2006 Jan 25;25(2):367-76. doi: 10.1038/sj.emboj.7600930. Epub 2006 Jan 12. EMBO J. 2006. PMID: 16407978 Free PMC article.
• A walk-through of the yeast mating pheromone response pathway.
  Bardwell L. Bardwell L. Peptides. 2005 Feb;26(2):339-50. doi: 10.1016/j.peptides.2004.10.002. Peptides. 2005. PMID: 15690603 Free PMC article. Review.
• Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast.
  Maleri S, Ge Q, Hackett EA, Wang Y, Dohlman HG, Errede B. Maleri S, et al. Mol Cell Biol. 2004 Oct;24(20):9221-38. doi: 10.1128/MCB.24.20.9221-9238.2004. Mol Cell Biol. 2004. PMID: 15456892 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • HighWire

• Other Literature Sources

  • The Lens - Patent Citations

• Molecular Biology Databases

  • BioCyc
  • Gene Ontology
  • Saccharomyces Genome Database