Obesity and all-cause mortality among black adults and white adults - PubMed (original) (raw)

. 2012 Sep 1;176(5):431-42.

doi: 10.1093/aje/kws032. Epub 2012 Jul 20.

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Obesity and all-cause mortality among black adults and white adults

Sarah S Cohen et al. Am J Epidemiol. 2012.

Abstract

In recent pooled analyses among whites and Asians, mortality was shown to rise markedly with increasing body mass index (BMI; weight (kg)/height (m)(2)), but much less is known about this association among blacks. This study prospectively examined all-cause mortality in relation to BMI among 22,014 black males, 9,343 white males, 30,810 black females, and 14,447 white females, aged 40-79 years, from the Southern Community Cohort Study, an epidemiologic cohort of largely low-income participants in 12 southeastern US states. Participants enrolled in the cohort from 2002 to 2009 and were followed up to 8.9 years. Hazard ratios and 95% confidence intervals for mortality were obtained from sex- and race-stratified Cox proportional hazards models in association with BMI at cohort entry, adjusting for age, education, income, cigarette smoking, and alcohol consumption. Elevated BMI was associated with increased mortality among whites (hazard ratios for BMI >40 vs. 20-24.9 = 1.37 (95% confidence interval (CI): 1.02, 1.84) and 1.47 (95% CI: 1.15, 1.89) for white males and white females, respectively) but not significantly among blacks (hazard ratios = 1.13 (95% CI: 0.89, 1.43) and 0.87 (95% CI: 0.72, 1.04) for black males and black females, respectively). In this large cohort, obesity in mid-to-late adulthood among blacks was not associated with the same excess mortality risk seen among whites.

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Figures

Figure 1.

Figure 1.

Hazard ratios for all-cause mortality by categories of body mass index at cohort entry for black adults and white adults by sex (females, top; males, bottom), Southern Community Cohort Study, 2002–2009. Cox proportional hazards models were adjusted for education, income, study enrollment source (community health center vs. general population), cigarette smoking, and alcohol consumption.

References

    1. Flegal KM, Carroll MD, Ogden CL, et al. Prevalence and trends in obesity among US adults, 1999–2008. JAMA. 2010;303(3):235–241. - PubMed
    1. Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of overweight and obesity in the United States, 1999–2004. JAMA. 2006;295(13):1549–1555. - PubMed
    1. Flegal KM, Carroll MD, Kuczmarski RJ, et al. Overweight and obesity in the United States: prevalence and trends, 1960–1994. Int J Obes Relat Metab Disord. 1998;22(1):39–47. - PubMed
    1. Calle EE, Thun MJ. Obesity and cancer. Oncogene. 2004;23(38):6365–6378. - PubMed
    1. Eckel RH, York DA, Rössner S, et al. Prevention Conference VII: obesity, a worldwide epidemic related to heart disease and stroke: executive summary. American Heart Association. Circulation. 2004;110(18):2968–2975. - PubMed

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