Body mass index and hospital mortality in patients with acute coronary syndrome receiving care in a university hospital - PubMed (original) (raw)

Body mass index and hospital mortality in patients with acute coronary syndrome receiving care in a university hospital

Mercedes Camprubi et al. J Obes. 2012.

Abstract

Although obesity is a well-established cardiovascular risk factor, some controversy has arisen with regard to its effect on hospital mortality in patients admitted for acute coronary syndrome. Methods. Clinical and anthropometric variables were analyzed in patients consecutively admitted for acute coronary syndrome to a university hospital between 2009 and 2010, and the correlation of those variables with hospital mortality was examined. Results. A total of 824 patients with a diagnosis of myocardial infarction or unstable angina were analyzed. Body mass index was an independent factor in hospital mortality (odds ratio 0.739 (IC 95%: 0.597 - 0.916), P = 0.006). Mortality in normal weight (n = 218), overweight (n = 399), and obese (n = 172) subjects was 6.1%, 3.1%, and 4.1%, respectively, with no statistically significant differences between the groups. Conclusions. There is something of a paradox in the relationship between body mass index and hospital mortality in patients with acute coronary syndrome in that the mortality rate decreases as body mass index increases. However, no statistically significant differences have been found in normal weight, overweight, or obese subjects.

PubMed Disclaimer

References

    1. Calle EE, Thun MJ, Petrelli JM, Rodriguez C, Heath CW., Jr. Body-mass index and mortality in a prospective cohort of U.S. adults. The New England Journal of Medicine. 1999;341(15):1097–1105. - PubMed
    1. Whitlock G, Lewington S, Sherliker P, et al. Body-mass index and cause-specific mortality in 900,000 adults: collaborative analyses of 57 prospective studies. The Lancet. 2009;373(9669):1083–1096. - PMC - PubMed
    1. Bays HE. Adiposopathy: is “sick fat” a cardiovascular disease? Journal of the American College of Cardiology. 2011;57(25):2461–2473. - PubMed
    1. -Medrano MJ, Pastor-Barriuso R, Boix R, et al. Riesgo coronario atribuible a los factores de riesgo cardiovascular en población española. Revista Española de Cardiología. 2007;60:1250–1256. - PubMed
    1. Buettner HJ, Mueller C, Gick M, et al. The impact of obesity on mortality in UA/non-ST-segment elevation myocardial infarction. European Heart Journal. 2007;28(14):1694–1701. - PubMed

LinkOut - more resources