Colony stimulating factors and myeloid cell biology in health and disease - PubMed (original) (raw)
Review
Colony stimulating factors and myeloid cell biology in health and disease
John A Hamilton et al. Trends Immunol. 2013 Feb.
Abstract
The colony stimulating factors (CSFs), granulocyte macrophage-CSF (GM-CSF), macrophage-CSF (M-CSF or CSF-1) and granulocyte-CSF (G-CSF) were first identified as in vitro hematopoietic growth factors. They have since been shown to regulate myeloid cell numbers and function at steady state and during inflammation. Preclinical data suggest that targeting CSFs might be beneficial in autoimmune and inflammatory disease, and manipulation of CSF biology is now being tested in clinical trials. Here, we examine recent insights into CSF function, at steady state and during pathology, as provided by CSF or CSF receptor neutralization/deletion studies or from CSF administration. We discuss controversies regarding the role of CSFs in controlling specific myeloid cell populations and highlight how the newly identified M-CSF receptor ligand, interleukin (IL)-34, is necessitating a reassessment of the field.
Copyright © 2012 Elsevier Ltd. All rights reserved.
Similar articles
- Regulation of myeloid development and function by colony stimulating factors.
Barreda DR, Hanington PC, Belosevic M. Barreda DR, et al. Dev Comp Immunol. 2004 May 3;28(5):509-54. doi: 10.1016/j.dci.2003.09.010. Dev Comp Immunol. 2004. PMID: 15062647 Review. - Regulation of differentiation of murine progenitor cells derived from blast cell colonies under serum-deprived conditions.
Migliaccio G, Migliaccio AR, Kaushansky K, Adamson JW. Migliaccio G, et al. Exp Hematol. 1989 Feb;17(2):110-5. Exp Hematol. 1989. PMID: 2463929 - Constitutive production of colony-stimulating factors by human hepatoma cell lines: possible correlation with cell differentiation.
Wang SY, Chen LY, Tsai TF, Su TS, Choo KB, Ho CK. Wang SY, et al. Exp Hematol. 1996 Feb;24(3):437-44. Exp Hematol. 1996. PMID: 8599973 - Biological role of granulocyte macrophage colony-stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) on cells of the myeloid lineage.
Ushach I, Zlotnik A. Ushach I, et al. J Leukoc Biol. 2016 Sep;100(3):481-9. doi: 10.1189/jlb.3RU0316-144R. Epub 2016 Jun 28. J Leukoc Biol. 2016. PMID: 27354413 Free PMC article. Review.
Cited by
- CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype-specific Vulnerability in IDH2- and TET2-mutant Cells.
Waarts MR, Mowla S, Boileau M, Martinez Benitez AR, Sango J, Bagish M, Fernández-Maestre I, Shan Y, Eisman SE, Park YC, Wereski M, Csete I, O'Connor K, Romero-Vega AC, Miles LA, Xiao W, Wu X, Koche RP, Armstrong SA, Shih AH, Papapetrou EP, Butler JM, Cai SF, Bowman RL, Levine RL. Waarts MR, et al. Cancer Discov. 2024 Oct 4;14(10):1860-1878. doi: 10.1158/2159-8290.CD-23-1092. Cancer Discov. 2024. PMID: 38819218 - Comparison of B cells' immune response induced by PEDV virulent and attenuated strains.
Yuan C, Zhao X, Feng Y, Chen L, Lin Y, Li T, Song Q. Yuan C, et al. Front Microbiol. 2024 Mar 22;15:1344344. doi: 10.3389/fmicb.2024.1344344. eCollection 2024. Front Microbiol. 2024. PMID: 38585694 Free PMC article. - Interleukins in Platelet Biology: Unraveling the Complex Regulatory Network.
Huang M, Wang L, Zhang Q, Zhou L, Liao R, Wu A, Wang X, Luo J, Huang F, Zou W, Wu J. Huang M, et al. Pharmaceuticals (Basel). 2024 Jan 13;17(1):109. doi: 10.3390/ph17010109. Pharmaceuticals (Basel). 2024. PMID: 38256942 Free PMC article. Review. - The evolution and heterogeneity of neutrophils in cancers: origins, subsets, functions, orchestrations and clinical applications.
Liu S, Wu W, Du Y, Yin H, Chen Q, Yu W, Wang W, Yu J, Liu L, Lou W, Pu N. Liu S, et al. Mol Cancer. 2023 Sep 7;22(1):148. doi: 10.1186/s12943-023-01843-6. Mol Cancer. 2023. PMID: 37679744 Free PMC article. Review. - The Role of Cytokines in Neutrophil Development, Tissue Homing, Function and Plasticity in Health and Disease.
Tsioumpekou M, Krijgsman D, Leusen JHW, Olofsen PA. Tsioumpekou M, et al. Cells. 2023 Jul 31;12(15):1981. doi: 10.3390/cells12151981. Cells. 2023. PMID: 37566060 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Research Materials
Miscellaneous