The history of dengue outbreaks in the Americas - PubMed (original) (raw)

The history of dengue outbreaks in the Americas

Olivia Brathwaite Dick et al. Am J Trop Med Hyg. 2012 Oct.

Abstract

Dengue is a viral disease usually transmitted by Aedes aegypti mosquitoes. Dengue outbreaks in the Americas reported in medical literature and to the Pan American Health Organization are described. The outbreak history from 1600 to 2010 was categorized into four phases: Introduction of dengue in the Americas (1600-1946); Continental plan for the eradication of the Ae. aegypti (1947-1970) marked by a successful eradication of the mosquito in 18 continental countries by 1962; Ae. aegypti reinfestation (1971-1999) caused by the failure of the mosquito eradication program; Increased dispersion of Ae. aegypti and dengue virus circulation (2000-2010) characterized by a marked increase in the number of outbreaks. During 2010 > 1.7 million dengue cases were reported, with 50,235 severe cases and 1,185 deaths. A dramatic increase in the number of outbreaks has been reported in recent years. Urgent global action is needed to avoid further disease spread.

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Conflict of interest statement

Disclosure: Betzana Zambrano and Gustavo H. Dayan are employees of Sanofi Pasteur, Inc. This statement is made in the interest of full disclosure and not because the authors consider this to be a conflict of interest. The manuscript was a collaboration between the authors. No funding was involved in the development of the manuscript. Information of this manuscript was presented at the 60th ASTMH Annual Meeting Philadelphia on December 5, 2011.

Figures

Figure 1.

Figure 1.

Evolution of dengue in the Americas, 1980–2010.

Figure 2.

Figure 2.

Number of dengue cases Ecuador, Paraguay, and Peru, 1995–2010.

Figure 3.

Figure 3.

Number of dengue cases Costa Rica, Paraguay, Brazil, Bolivia, Argentina, Mexico, and Nicaragua, 1995–2010.

Figure 4.

Figure 4.

Dengue incidence in the Americas, 1980–2010.

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