Intramuscular adipose tissue and central activation in older adults - PubMed (original) (raw)
Intramuscular adipose tissue and central activation in older adults
Yuri Yoshida et al. Muscle Nerve. 2012 Nov.
Abstract
Introduction: Intramuscular adipose tissue (IMAT) is a potential contributor to declining force production and may be related to impaired central activation; therefore, the purpose of this report is to describe IMAT composition and its association with central activation in older adults. The central activation ratio (CAR) of the knee extensors was assessed using a superimposition technique in 15 older adults (29 legs) along with the cross-sectional area of IMAT and lean tissue.
Results: IMAT and CAR are inversely related in older adults (r = -0.51, P = 0.005), and many subjects with high IMAT have deficits in central activation, whereas those with low IMAT have normal central activation.
Conclusions: These novel findings may assist in unraveling why muscle force production and lean tissue cross-sectional area are not strongly linked, as the ability to centrally activate muscle appears to be unrelated to lean muscle area and may be dependent in part on IMAT levels.
Copyright © 2012 Wiley Periodicals, Inc.
Similar articles
- Intramuscular adipose tissue attenuates gains in muscle quality in older adults at high risk for falling. A brief report.
Marcus RL, Addison O, LaStayo PC. Marcus RL, et al. J Nutr Health Aging. 2013 Mar;17(3):215-8. doi: 10.1007/s12603-012-0377-5. J Nutr Health Aging. 2013. PMID: 23459972 - Intramuscular fat and inflammation differ in older adults: the impact of frailty and inactivity.
Addison O, Drummond MJ, LaStayo PC, Dibble LE, Wende AR, McClain DA, Marcus RL. Addison O, et al. J Nutr Health Aging. 2014 May;18(5):532-8. doi: 10.1007/s12603-014-0019-1. J Nutr Health Aging. 2014. PMID: 24886741 Free PMC article. - Associations of Quadriceps Torque Properties with Muscle Size, Attenuation, and Intramuscular Adipose Tissue in Older Adults.
Frank-Wilson AW, Chalhoub D, Figueiredo P, Jónsson PV, Siggeirsdóttir K, Sigurdsson S, Eiriksdottir G, Guðnason V, Launer L, Harris TB; AGES-Reykjavik Study. Frank-Wilson AW, et al. J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):931-938. doi: 10.1093/gerona/glx262. J Gerontol A Biol Sci Med Sci. 2018. PMID: 29342246 Free PMC article. - The Metabolic Significance of Intermuscular Adipose Tissue: Is IMAT a Friend or a Foe to Metabolic Health?
Sparks LM, Goodpaster BH, Bergman BC. Sparks LM, et al. Diabetes. 2021 Nov;70(11):2457-2467. doi: 10.2337/dbi19-0006. Diabetes. 2021. PMID: 34711670 Review. - Aging human body: changes in bone, muscle and body fat with consequent changes in nutrient intake.
JafariNasabian P, Inglis JE, Reilly W, Kelly OJ, Ilich JZ. JafariNasabian P, et al. J Endocrinol. 2017 Jul;234(1):R37-R51. doi: 10.1530/JOE-16-0603. Epub 2017 Apr 25. J Endocrinol. 2017. PMID: 28442508 Review.
Cited by
- The effects of myosteatosis on skeletal muscle function in older adults.
Dondero K, Friedman B, Rekant J, Landers-Ramos R, Addison O. Dondero K, et al. Physiol Rep. 2024 May;12(9):e16042. doi: 10.14814/phy2.16042. Physiol Rep. 2024. PMID: 38705872 Free PMC article. Review. - Exploring the nexus between fatigue, body composition, and muscle strength in hemodialysis patients.
Shi R, Zhu JX, Zhu L, Zhao WM, Li H, Chen QC, Pan HF, Wang DG. Shi R, et al. Eur J Med Res. 2024 May 3;29(1):266. doi: 10.1186/s40001-024-01852-1. Eur J Med Res. 2024. PMID: 38698469 Free PMC article. - Exploring the Relationship between Ultrasonographic Measures of the Quadriceps and Knee Extensor Muscle Fitness in Endurance-Trained Individuals.
Voskuil CC, Dudar MD, Carr JC. Voskuil CC, et al. Transl Sports Med. 2024 Apr 8;2024:3415740. doi: 10.1155/2024/3415740. eCollection 2024. Transl Sports Med. 2024. PMID: 38654724 Free PMC article. - Mid-life cyclists preserve muscle mass and composition: a 3D MRI study.
Belzunce MA, Henckel J, Laura AD, Horga LM, Hart AJ. Belzunce MA, et al. BMC Musculoskelet Disord. 2023 Mar 20;24(1):209. doi: 10.1186/s12891-023-06283-3. BMC Musculoskelet Disord. 2023. PMID: 36941610 Free PMC article. - Relative contribution of neuromuscular activation, muscle size, and muscle quality to maximum strength output of the thigh muscles in young individuals.
Yoshiko A, Watanabe K, Akima H. Yoshiko A, et al. Physiol Rep. 2023 Jan;11(1):e15563. doi: 10.14814/phy2.15563. Physiol Rep. 2023. PMID: 36597223 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical