Efficiency of biolistic DNA vaccination in experimental type I allergy - PubMed (original) (raw)
Efficiency of biolistic DNA vaccination in experimental type I allergy
Verena Raker et al. Methods Mol Biol. 2013.
Abstract
Gene gun-mediated delivery of allergen-encoding plasmid DNA has been in focus for many years now as being a needle-free alternative to the protein-based desensitization regimen used in specific immunotherapy. Biolistic immunization with the Helios gene gun has proven to be potent in the induction of antigen-specific CD4(+) and CD8(+) T cells. Here we describe biolistic vaccination in experimental mouse models of IgE-mediated type I allergy as well as allergen-induced airway inflammation.
Similar articles
- Prevention of long-term IgE antibody production by gene gun-mediated DNA vaccination.
Ludwig-Portugall I, Montermann E, Kremer A, Reske-Kunz AB, Sudowe S. Ludwig-Portugall I, et al. J Allergy Clin Immunol. 2004 Oct;114(4):951-7. doi: 10.1016/j.jaci.2004.06.013. J Allergy Clin Immunol. 2004. PMID: 15480341 - Prophylactic and therapeutic intervention in IgE responses by biolistic DNA vaccination primarily targeting dendritic cells.
Sudowe S, Ludwig-Portugall I, Montermann E, Ross R, Reske-Kunz AB. Sudowe S, et al. J Allergy Clin Immunol. 2006 Jan;117(1):196-203. doi: 10.1016/j.jaci.2005.08.058. Epub 2005 Nov 8. J Allergy Clin Immunol. 2006. PMID: 16387606 - Gene gun immunization with clinically relevant allergens aggravates allergen induced pathology and is contraindicated for allergen immunotherapy.
Scheiblhofer S, Stoecklinger A, Gruber C, Hauser-Kronberger C, Alinger B, Hammerl P, Thalhamer J, Weiss R. Scheiblhofer S, et al. Mol Immunol. 2007 Mar;44(8):1879-87. doi: 10.1016/j.molimm.2006.09.023. Epub 2006 Oct 30. Mol Immunol. 2007. PMID: 17070909 - DNA vaccines for allergy treatment.
Weiss R, Scheiblhofer S, Thalhamer J. Weiss R, et al. Methods Mol Med. 2006;127:253-67. doi: 10.1385/1-59745-168-1:253. Methods Mol Med. 2006. PMID: 16988459 Review. - [DNA vaccines against allergy].
Sato Y, Kasukawa R. Sato Y, et al. Nihon Rinsho. 2000 Jun;58(6):1307-14. Nihon Rinsho. 2000. PMID: 10879058 Review. Japanese.
Cited by
- DNA Vaccines-How Far From Clinical Use?
Hobernik D, Bros M. Hobernik D, et al. Int J Mol Sci. 2018 Nov 15;19(11):3605. doi: 10.3390/ijms19113605. Int J Mol Sci. 2018. PMID: 30445702 Free PMC article. Review. - Nucleic Acid-Based Approaches for Tumor Therapy.
Hager S, Fittler FJ, Wagner E, Bros M. Hager S, et al. Cells. 2020 Sep 9;9(9):2061. doi: 10.3390/cells9092061. Cells. 2020. PMID: 32917034 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials