Outcomes using lower vs higher hemoglobin thresholds for red blood cell transfusion - PubMed (original) (raw)
Comment
. 2013 Jan 2;309(1):83-4.
doi: 10.1001/jama.2012.50429.
Affiliations
- PMID: 23280228
- DOI: 10.1001/jama.2012.50429
Comment
Outcomes using lower vs higher hemoglobin thresholds for red blood cell transfusion
Jeffrey L Carson et al. JAMA. 2013.
Abstract
Clinical question: Is a lower vs higher hemoglobin threshold best for minimizing both red blood cell use and adverse clinical outcomes when used to trigger red blood cell transfusions in anemic patients in critical care and acute care settings?
Bottom line: Compared with higher hemoglobin thresholds, a hemoglobin threshold of 7 or 8 g/dL is associated with fewer red blood cell units transfused without adverse associations with mortality, cardiac morbidity, functional recovery, or length of hospital stay.
Comment on
- Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion.
Carson JL, Carless PA, Hebert PC. Carson JL, et al. Cochrane Database Syst Rev. 2012 Apr 18;4(4):CD002042. doi: 10.1002/14651858.CD002042.pub3. Cochrane Database Syst Rev. 2012. PMID: 22513904 Free PMC article. Updated. Review.
Similar articles
- Efficacy of recombinant human erythropoietin in critically ill patients admitted to a long-term acute care facility: a randomized, double-blind, placebo-controlled trial.
Silver M, Corwin MJ, Bazan A, Gettinger A, Enny C, Corwin HL. Silver M, et al. Crit Care Med. 2006 Sep;34(9):2310-6. doi: 10.1097/01.CCM.0000233873.17954.42. Crit Care Med. 2006. PMID: 16878035 Clinical Trial. - [Transfusion of recuperated blood in total knee arthroplasty].
Pitsaer E. Pitsaer E. Rev Chir Orthop Reparatrice Appar Mot. 2002 Dec;88(8):777-89. Rev Chir Orthop Reparatrice Appar Mot. 2002. PMID: 12503019 French. - Continuous and noninvasive hemoglobin monitoring reduces red blood cell transfusion during neurosurgery: a prospective cohort study.
Awada WN, Mohmoued MF, Radwan TM, Hussien GZ, Elkady HW. Awada WN, et al. J Clin Monit Comput. 2015 Dec;29(6):733-40. doi: 10.1007/s10877-015-9660-4. Epub 2015 Feb 4. J Clin Monit Comput. 2015. PMID: 25649717 Free PMC article. Clinical Trial. - Should we reconsider triggers for red blood cell transfusion?
Hardy JF. Hardy JF. Acta Anaesthesiol Belg. 2003;54(4):287-95. Acta Anaesthesiol Belg. 2003. PMID: 14719346 Review. - Critically ill children: to transfuse or not to transfuse packed red blood cells, that is the question.
Tyrrell CT, Bateman ST. Tyrrell CT, et al. Pediatr Crit Care Med. 2012 Mar;13(2):204-9. doi: 10.1097/PCC.0b013e318219291c. Pediatr Crit Care Med. 2012. PMID: 21499178 Review.
Cited by
- Assessment of hematologic parameters before and after bimaxillary orthognathic surgery.
Chrcanovic BR, Toledo GL, Amaral MB, Custódio AL. Chrcanovic BR, et al. Oral Maxillofac Surg. 2016 Mar;20(1):35-43. doi: 10.1007/s10006-015-0525-2. Epub 2015 Aug 18. Oral Maxillofac Surg. 2016. PMID: 26280080 Clinical Trial. - Restrictive vs. Liberal Red Blood Cell Transfusion Strategy in Patients With Acute Myocardial Infarction and Anemia: A Systematic Review and Meta-Analysis.
Zhang Y, Xu Z, Huang Y, Ye Q, Xie N, Zeng L, Lian X, Dai Y, Chen J, He P, Tan N, Liu Y. Zhang Y, et al. Front Cardiovasc Med. 2021 Nov 16;8:736163. doi: 10.3389/fcvm.2021.736163. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 34869640 Free PMC article. - Mortality and treatment patterns among patients hospitalized with acute cardiovascular conditions during dates of national cardiology meetings.
Jena AB, Prasad V, Goldman DP, Romley J. Jena AB, et al. JAMA Intern Med. 2015 Feb;175(2):237-44. doi: 10.1001/jamainternmed.2014.6781. JAMA Intern Med. 2015. PMID: 25531231 Free PMC article. - Utilisation of Blood Components in Trauma Surgery: A Single-Centre, Retrospective Analysis before and after the Implementation of an Educative PBM Initiative.
Geissler RG, Kösters C, Franz D, Buddendick H, Borowski M, Juhra C, Lange M, Bunzemeier H, Roeder N, Sibrowski W, Raschke MJ, Schlenke P. Geissler RG, et al. Transfus Med Hemother. 2015 Mar;42(2):83-9. doi: 10.1159/000377735. Epub 2015 Mar 12. Transfus Med Hemother. 2015. PMID: 26019703 Free PMC article. - Evaluation and management of anemia in the elderly.
Goodnough LT, Schrier SL. Goodnough LT, et al. Am J Hematol. 2014 Jan;89(1):88-96. doi: 10.1002/ajh.23598. Am J Hematol. 2014. PMID: 24122955 Free PMC article. Review.
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources