Chronic granulomatous disease - PubMed (original) (raw)

Review

Chronic granulomatous disease

Steven M Holland. Hematol Oncol Clin North Am. 2013 Feb.

Abstract

Chronic granulomatous disease (CGD) is a paradigm for nonlymphoid primary immune defects, and has guided elucidation of oxygen metabolism in the phagocyte, vasculature, and brain. It has been in the forefront of the development of antimicrobial prophylaxis before the advent of advanced HIV and before its routine use in neutropenia. It has been an attractive target for gene therapy and bone marrow transplantation for nonmalignant diseases. Therefore, CGD is worthy of attention for its historical interest and because it is a disease for which expert management is imperative.

Published by Elsevier Inc.

PubMed Disclaimer

References

    1. Janeway CA, Craig J, Davidson M, Downey W, Gitlin D, Sullivan JC. Hypergammaglobulinemia associated with severe, recurrent and chronic non-specific infection. Am J Dis Child. 1954;88:388–392.
    1. Berendes H, Bridges RA, Good RA. A fatal granulomatous disease of childhood: The clinical study of a new syndrome. Minn Med. 1957;40:309. - PubMed
    1. Bruton OC. Agammaglobulinemia. Pediatrics. 1952 Jun;9(6):722–8. - PubMed
    1. Bridges RA, Berendes H, Good RA. A fatal granulomatous disease of childhood. Am J Dis Child. 1959;97:387. - PubMed
    1. Azimi PH, Bodenbender JG, Hintz RL, Kontras SB. Chronic granulomatous disease in three female siblings. JAMA. 1968;206:2865–70. - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources