In vitro-synthesized hepatitis delta virus RNA initiates genome replication in cultured cells - PubMed (original) (raw)

In vitro-synthesized hepatitis delta virus RNA initiates genome replication in cultured cells

J S Glenn et al. J Virol. 1990 Jun.

Abstract

Monomers of the genomic strand of hepatitis delta virus RNA were transcribed in vitro and then delivered to NIH 3T3 fibroblasts by using a liposome fusion technique. After 7 days, genome replication was detected, but only in fibroblasts that stably expressed the delta antigen. Sequence analysis of the replicated products identified them as faithful copies of the hepatitis delta virus genome found in virions.

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References

1. 1. J Virol. 1972 Aug;10(2):297-309 - PubMed
2. 1. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7 - PubMed
3. 1. Hepatology. 1983 Sep-Oct;3(5):729-37 - PubMed
4. 1. Science. 1984 Feb 3;223(4635):450-5 - PubMed
5. 1. Infect Immun. 1984 Mar;43(3):1000-5 - PubMed

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