Eccrine carcinoma : a rare cutaneous neoplasm - PubMed (original) (raw)

Case Reports

Eccrine carcinoma : a rare cutaneous neoplasm

Karima Idrissi Serhrouchni et al. Diagn Pathol. 2013.

Abstract

Eccrine carcinoma is an extremely rare malignancy of the skin with few well documented cases reported in the literature. It is frequently found on the lower extremities, and it equally affects both sexes in the sixth and seventh decade.In our case, we present a 46- year-old female with a recurring exophytic tumor on the right lower extremity, without local extension.The initial tumor was biopsied, excised and diagnosed as an eccrine carcinoma.

Virtual slides: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/3568051328673318.

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Figures

Figure 1

Clinical picture showed an ulcerative and bourgeoning mass of 15 cm with bleeding and purulent features on the posterior right lower extremity.

Figure 2

An undifferentiated malignant proliferation with nodular architecture, located in the deep dermis (hematoxylin-eosin, original magnification: x 100).

Figure 3

Tumor cells made clear cytoplasm with an hyperchromatic nucleus and a high mitotic activity (hematoxylin-eosin, original magnification: A, × 200, B, x 400).

Figure 4

Immunohistochemical study showing reactivity for CK (A), CK7 (B) and progesterone receptors (C).

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Eccrine carcinoma : a rare cutaneous neoplasm - PubMed (original) (raw)