Small RNA-directed silencing: the fly finds its inner fission yeast? - PubMed (original) (raw)
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. 2013 Apr 22;23(8):R318-20.
doi: 10.1016/j.cub.2013.03.033.
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- PMID: 23618667
- DOI: 10.1016/j.cub.2013.03.033
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Small RNA-directed silencing: the fly finds its inner fission yeast?
Daniel Tianfang Ge et al. Curr Biol. 2013.
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Abstract
Several recent studies demonstrate that piRNAs guide Piwi protein to repress transposon transcription in fly ovaries, much as fission yeast use siRNAs to silence repeat sequences. Still mysterious though is how Piwi targets euchromatic transposons for silencing, but not the specialized heterochromatic loci that produce piRNA precursors.
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