Long-term prognostic value of white coat hypertension: an insight from diagnostic use of both ambulatory and home blood pressure measurements - PubMed (original) (raw)
Comparative Study
Long-term prognostic value of white coat hypertension: an insight from diagnostic use of both ambulatory and home blood pressure measurements
Giuseppe Mancia et al. Hypertension. 2013 Jul.
Abstract
The prognostic value of white coat hypertension (WCH) is still debated. In 2051 subjects representative of the general population of Monza, we measured office, ambulatory, and home blood pressure (BP). The risk of cardiovascular and all-cause mortality was assessed over 16 years in normotensive, sustained hypertensive, and WCH subjects, the last group being defined as usually done in clinical practice (ie, by normality of 1 out-of-office [ambulatory or home] BP with an office BP elevation). Compared with normotensive subjects, the risk of cardiovascular mortality, as adjusted for potential confounders, showed a progressive significant increase in WCH and sustained hypertensive subjects (2.04 and 2.94; P=0.006). In either group, a significant increase in adjusted risk was also seen for all-cause mortality. However, when the WCH group was subdivided into 2 subgroups, that is, subjects in whom both out-of-office BPs were normal (true WCH, 42%) or one BP was normal whereas the other was elevated (partial WCH, 58%), only the latter showed a significantly greater adjusted risk of cardiovascular and all-cause mortality (2.76 and 1.58; P<0.03). Compared with normotensive subjects, the partial WCH group also exhibited a marked increase in adjusted risk of developing sustained hypertension over a 10-year time period (2.58; P<0.0001), but in this case the risk was also increased in true WCH subjects (2.89; P<0.0001). Thus, WCH includes subjects with a widely different long-term risk of a cardiovascular event. To identify those at higher risk, measurements of both out-of-office BPs are desirable.
Keywords: ambulatory blood pressure monitoring; home blood pressure monitoring; mortality; prognosis; white coat hypertension.
Comment in
- Definition of white coat hypertension: ambulatory blood pressure, self-measured blood pressure, or both?
de la Sierra A. de la Sierra A. Hypertension. 2013 Jul;62(1):16-7. doi: 10.1161/HYPERTENSIONAHA.113.01565. Epub 2013 May 28. Hypertension. 2013. PMID: 23716585 No abstract available.
Similar articles
- Adverse prognostic value of persistent office blood pressure elevation in white coat hypertension.
Mancia G, Facchetti R, Grassi G, Bombelli M. Mancia G, et al. Hypertension. 2015 Aug;66(2):437-44. doi: 10.1161/HYPERTENSIONAHA.115.05367. Epub 2015 Jun 8. Hypertension. 2015. PMID: 26056342 - Prognostic significance of masked and white-coat hypertension in the general population: the Finn-Home Study.
Hänninen MR, Niiranen TJ, Puukka PJ, Johansson J, Jula AM. Hänninen MR, et al. J Hypertens. 2012 Apr;30(4):705-12. doi: 10.1097/HJH.0b013e328350a69b. J Hypertens. 2012. PMID: 22278146 - Prognosis of white-coat and masked hypertension: International Database of HOme blood pressure in relation to Cardiovascular Outcome.
Stergiou GS, Asayama K, Thijs L, Kollias A, Niiranen TJ, Hozawa A, Boggia J, Johansson JK, Ohkubo T, Tsuji I, Jula AM, Imai Y, Staessen JA; International Database on HOme blood pressure in relation to Cardiovascular Outcome (IDHOCO) Investigators. Stergiou GS, et al. Hypertension. 2014 Apr;63(4):675-82. doi: 10.1161/HYPERTENSIONAHA.113.02741. Epub 2014 Jan 13. Hypertension. 2014. PMID: 24420553 - [White-coat hypertension].
Yamashita S. Yamashita S. Nihon Rinsho. 2014 Aug;72(8):1410-4. Nihon Rinsho. 2014. PMID: 25167744 Review. Japanese. - [White-coat hypertension and masked hypertension].
Filipovský J. Filipovský J. Vnitr Lek. 2015 May;61(5):401-5. Vnitr Lek. 2015. PMID: 26075847 Review. Czech.
Cited by
- White Coat Hypertension & Cardiovascular Outcomes.
Townsend RR, Cohen JB. Townsend RR, et al. Curr Hypertens Rep. 2024 Oct;26(10):399-407. doi: 10.1007/s11906-024-01309-0. Epub 2024 May 18. Curr Hypertens Rep. 2024. PMID: 38761349 Free PMC article. Review. - Effects of Nondipping Blood Pressure Changes: A Nephrologist Prospect.
Habas E Sr, Akbar RA, Alfitori G, Farfar KL, Habas E, Errayes N, Habas A, Al Adab A, Rayani A, Geryo N, Elzouki AY. Habas E Sr, et al. Cureus. 2023 Jul 30;15(7):e42681. doi: 10.7759/cureus.42681. eCollection 2023 Jul. Cureus. 2023. PMID: 37649932 Free PMC article. Review. - The long-term reproducibility of the white-coat effect on blood pressure as a continuous variable from the Ohasama Study.
Satoh M, Yoshida T, Metoki H, Murakami T, Tatsumi Y, Hirose T, Takabatake K, Tsubota-Utsugi M, Hara A, Nomura K, Asayama K, Kikuya M, Hozawa A, Imai Y, Ohkubo T. Satoh M, et al. Sci Rep. 2023 Mar 27;13(1):4985. doi: 10.1038/s41598-023-31861-9. Sci Rep. 2023. PMID: 36973366 Free PMC article. - Feasibility of Precision Medicine in Hypertension Management-Scope and Technological Aspects.
Nitzan M, Nitzan I. Nitzan M, et al. J Pers Med. 2022 Nov 7;12(11):1861. doi: 10.3390/jpm12111861. J Pers Med. 2022. PMID: 36573720 Free PMC article. - Antihypertensive drug treatment in white-coat hypertension: data from the Plaque HYpertension Lipid-Lowering Italian Study.
Mancia G, Facchetti R, Quarti-Trevano F, Grassi G. Mancia G, et al. J Hypertens. 2022 Oct 1;40(10):1909-1917. doi: 10.1097/HJH.0000000000003176. Epub 2022 Jul 25. J Hypertens. 2022. PMID: 35881420 Free PMC article. Clinical Trial.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources