L-tryptophan metabolism in pregnant mice fed a high L-tryptophan diet and the effect on maternal, placental, and fetal growth - PubMed (original) (raw)

Figure 2

Increase in Non-proteinaceous form of L-Trp concentrations in liver, blood, placenta, and fetus at E12.5 and E17.5 in the pregnant mice fed the 5% L-Trp diets (experiment 1). Notes: Non-proteinaceous form of L-Trp concentrations of maternal liver (A) (control, n = 5; 2% L-Trp, n = 3; 5% L-Trp, n = 4), blood (B) (control, n = 5; 2% L-Trp, n = 3; 5% L-Trp, n = 5), placenta (C) (control, n = 14; 2% L-Trp, n = 7; 5% L-Trp, n = 10) and fetus (D) (control, n = 17; 2% L-Trp, n = 8; 5% L-Trp, n = 15) at E12.5. Non-proteinaceous form of L-Trp concentrations of maternal liver (E) (control, n = 6; 2% L-Trp, n = 4; 5% L-Trp, n = 3), blood (F) (control, n = 6; 2% L-Trp, n = 4; 5% L-Trp, n = 4), placenta (G) (control, n = 10; 2% L-Trp, n = 9; 5% L-Trp, n = 10) and fetus (H) (control, n = 14; 2% L-Trp, n = 13; 5% L-Trp, n = 16) at E17.5. Ctrl, control group; 2% L-Trp, the 2% L-Trp group; 5% L-Trp, the 5% L-Trp group. Values are mean ± SE. Values that do not share the same superscript letters are significantly different by one-way ANOVA with Tukey’s multiple comparison tests (P < 0.05).