Tissue clearing for optical anatomy - PubMed (original) (raw)

Comparative Study

. 2013 Oct 11;52(42):10949-51.

doi: 10.1002/anie.201306039. Epub 2013 Sep 3.

Affiliations

• PMID: 24038881
• DOI: 10.1002/anie.201306039

Comparative Study

Tissue clearing for optical anatomy

Dmytro A Yushchenko et al. Angew Chem Int Ed Engl. 2013.

Abstract

Quest for transparency: Detailed optical imaging of complex biological entities remains an unmet goal mainly because of the light scattering of biological tissue. A new approach to tissue clearing termed CLARITY is getting us closer to an anatomical view of thick tissues and entire organs with cellular resolution.

Keywords: fluorescence imaging; light scattering; microscopy; tissue clearing.

Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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