MicroRNA-148a: a potential therapeutic target for cancer - PubMed (original) (raw)
. 2014 Jan 1;533(1):456-7.
doi: 10.1016/j.gene.2013.09.067. Epub 2013 Sep 29.
Affiliations
- PMID: 24084367
- DOI: 10.1016/j.gene.2013.09.067
MicroRNA-148a: a potential therapeutic target for cancer
Zhaolin Chen et al. Gene. 2014.
Abstract
MicroRNA-148a (miR-148a) which suppresses tumor growth by directly decreasing DNMT1 expression has been demonstrated as an important role for cancer therapy. The mechanisms for miR-148a in cancer will become potential future researches.
Keywords: CAFs; DNA methyltransferase 1; DNMT1; HCC; NFs; RUNX3; Runt-related transcription factor 3; cancer-associated fibroblasts; hepatocellular carcinoma; miR-148a; microRNA-148a; normal tissue fibroblasts.
© 2013 Elsevier B.V. All rights reserved.
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