Cardiac rehabilitation and outcome in stable outpatients with recent myocardial infarction - PubMed (original) (raw)
doi: 10.1016/j.apmr.2013.09.020. Epub 2013 Oct 9.
Ramon Coll 2, Teresa Pascual 3, J Francisco Sánchez Muñoz-Torrero 4, Joan Carles Sahuquillo 5, Luis Manzano 6, Eduardo Aguilar 7, José N Alcala-Pedrajas 8, Lorenzo Ramón Alvarez 9, Ana María García-Díaz 10, Abel Mujal 11, Montserrat Yeste 12, Manuel Monreal 13
Affiliations
- PMID: 24121084
- DOI: 10.1016/j.apmr.2013.09.020
Cardiac rehabilitation and outcome in stable outpatients with recent myocardial infarction
Roser Coll-Fernández et al. Arch Phys Med Rehabil. 2014 Feb.
Abstract
Objective: To compare the mortality rate and the rate of subsequent ischemic events (myocardial infarction [MI], ischemic stroke, or limb amputation) in patients with recent MI according to the use of cardiac rehabilitation or no rehabilitation.
Design: Longitudinal observational study.
Setting: Ongoing registry of outpatients.
Participants: Patients (N=1043) with recent acute MI were recruited; of these, 521 (50%) participated in cardiac rehabilitation.
Interventions: Not applicable.
Main outcome measures: Subsequent ischemic events and mortality rates were registered.
Results: Over a mean follow-up of 18 months, 50 patients (4.8%) died and 49 (4.7%) developed 52 subsequent ischemic events (MI: n=43, ischemic stroke: n=6, limb amputation: n=3). Both the mortality rate (.16 vs 5.57 deaths per 100 patient-years; rate ratio=.03; 95% confidence interval [CI], 0.0-0.1]) and the rate of subsequent ischemic events (1.65 vs 4.54 events per 100 patient-years; rate ratio=0.4; 95% CI, 0.2-0.7) were significantly lower in cardiac rehabilitation participants than in nonparticipants. Multivariate analysis confirmed that patients in cardiac rehabilitation had a significantly lower risk of death (hazard ratio=.08; 95% CI, .01-.63; P=.016) and a nonsignificant lower risk of subsequent ischemic events (hazard ratio=.65; 95% CI, .30-1.42).
Conclusions: The use of cardiac rehabilitation in patients with recent MI was independently associated with a significant decrease in the mortality rate and a nonsignificant decrease in the rate of subsequent ischemic events.
Keywords: CI; FRENA; MI; Risk Factors and Arterial Disease; confidence interval; myocardial infarction.
Copyright © 2014 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
Similar articles
- Supervised versus non-supervised exercise in patients with recent myocardial infarction: A propensity analysis.
Coll-Fernández R, Coll R, Muñoz-Torrero JF, Aguilar E, Ramón Álvarez L, Sahuquillo JC, Yeste M, Jiménez PE, Mujal A, Monreal M; FRENA Investigators. Coll-Fernández R, et al. Eur J Prev Cardiol. 2016 Feb;23(3):245-52. doi: 10.1177/2047487315578443. Epub 2015 Mar 23. Eur J Prev Cardiol. 2016. PMID: 25802422 - Predictors of outcome in stable outpatients with peripheral artery disease.
Sanclemente C, Yeste M, Suarez C, Coll R, Aguilar E, Sahuquillo JC, Lerma R, Monreal M; FRENA investigators. Sanclemente C, et al. Intern Emerg Med. 2014 Feb;9(1):69-77. doi: 10.1007/s11739-012-0854-1. Epub 2012 Sep 29. Intern Emerg Med. 2014. PMID: 23054402 - Renal function and short-term outcome in stable outpatients with coronary, cerebrovascular or peripheral artery disease.
Bernaudo D, Coll R, Sánchez Muñoz-Torrero JF, Pascual MT, García-Díaz AM, Alvarez LR, Monreal M; FRENA Investigators. Bernaudo D, et al. Atherosclerosis. 2013 Jul;229(1):258-62. doi: 10.1016/j.atherosclerosis.2013.04.029. Epub 2013 May 9. Atherosclerosis. 2013. PMID: 23714334 - Depression, stroke, and dementia in patients with myocardial infarction.
Sundbøll J. Sundbøll J. Dan Med J. 2018 Apr;65(4):B5423. Dan Med J. 2018. PMID: 29619929 Review. - Home-based versus centre-based cardiac rehabilitation.
Taylor RS, Dalal H, Jolly K, Zawada A, Dean SG, Cowie A, Norton RJ. Taylor RS, et al. Cochrane Database Syst Rev. 2015 Aug 18;(8):CD007130. doi: 10.1002/14651858.CD007130.pub3. Cochrane Database Syst Rev. 2015. PMID: 26282071 Updated. Review.
Cited by
- [Analysis of the status of cardiac rehabilitation in Spain: an exploratory review].
Pujalte MF, Richart-Martínez M, Perpiñá-Galvañ J. Pujalte MF, et al. An Sist Sanit Navar. 2022 Apr 27;45(1):e0991. doi: 10.23938/ASSN.0991. An Sist Sanit Navar. 2022. PMID: 35043786 Free PMC article. Review. Spanish. - Predicting Long-Term Mortality, Morbidity, and Survival Outcomes Following a Cardiac Event: A Cardiac Rehabilitation Study.
Graham HL, Lac A, Lee H, Benton MJ. Graham HL, et al. Rehabil Process Outcome. 2019 Feb 17;8:1179572719827610. doi: 10.1177/1179572719827610. eCollection 2019. Rehabil Process Outcome. 2019. PMID: 34497458 Free PMC article. - Effects of Exercise-Based Cardiac Rehabilitation in Patients with Acute Coronary Syndrome: A Meta-Analysis.
Ji H, Fang L, Yuan L, Zhang Q. Ji H, et al. Med Sci Monit. 2019 Jul 7;25:5015-5027. doi: 10.12659/MSM.917362. Med Sci Monit. 2019. PMID: 31280281 Free PMC article. - The prognostic effect of cardiac rehabilitation in the era of acute revascularisation and statin therapy: A systematic review and meta-analysis of randomized and non-randomized studies - The Cardiac Rehabilitation Outcome Study (CROS).
Rauch B, Davos CH, Doherty P, Saure D, Metzendorf MI, Salzwedel A, Völler H, Jensen K, Schmid JP; ‘Cardiac Rehabilitation Section’, European Association of Preventive Cardiology (EAPC), in cooperation with the Institute of Medical Biometry and Informatics (IMBI), Department of Medical Biometry, University of Heidelberg, and the Cochrane Metabolic and Endocrine Disorders Group, Institute of General Practice, Heinrich-Heine University, Düsseldorf, Germany. Rauch B, et al. Eur J Prev Cardiol. 2016 Dec;23(18):1914-1939. doi: 10.1177/2047487316671181. Epub 2016 Oct 25. Eur J Prev Cardiol. 2016. PMID: 27777324 Free PMC article. Review. - Effectiveness of comprehensive cardiac rehabilitation in coronary artery disease patients treated according to contemporary evidence based medicine: Update of the Cardiac Rehabilitation Outcome Study (CROS-II).
Salzwedel A, Jensen K, Rauch B, Doherty P, Metzendorf MI, Hackbusch M, Völler H, Schmid JP, Davos CH. Salzwedel A, et al. Eur J Prev Cardiol. 2020 Nov;27(16):1756-1774. doi: 10.1177/2047487320905719. Epub 2020 Feb 23. Eur J Prev Cardiol. 2020. PMID: 32089005 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical