Oral microbiota and systemic disease - PubMed (original) (raw)
Review
Oral microbiota and systemic disease
Purnima S Kumar. Anaerobe. 2013 Dec.
Abstract
It is well known that bacteria are the primary cause of infectious diseases, however, evidence is emerging that these organisms are also indirectly responsible for several diseases including cancer and rheumatoid arthritis. The oral cavity is home to several million bacteria that can cause two major diseases-periodontitis and caries. The relationship between periodontopathic bacteria and systemic diseases has been explored for several years. The concept of the oral cavity as a source of distant infection has been debated for at least a century. This review will discuss the historic aspects of the development of the focal infection theory, the reasons for its demise, its re-emergence and current status.
Keywords: Focal infection; Focal sepsis; Oral bacteria; Periodontal medicine; Systemic disease.
Copyright © 2013 Elsevier Ltd. All rights reserved.
Comment in
- Oral microbiota change, tooth decay and hemorrhoidal disease.
Ozkan B, Topuk SN, Taser N, Filik L. Ozkan B, et al. Anaerobe. 2015 Jun;33:137. doi: 10.1016/j.anaerobe.2015.03.007. Epub 2015 Mar 26. Anaerobe. 2015. PMID: 25817607 No abstract available.
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