Efficient replication of HTLV-III and STLV-IIImac in human Jurkat cells - PubMed (original) (raw)
Efficient replication of HTLV-III and STLV-IIImac in human Jurkat cells
I Wendler et al. Med Microbiol Immunol. 1987.
Abstract
High producer cell lines were established by infecting Jurkat cells with either HTLV-IIIB from H9 cells or with STLV-IIImac from HUT-78 cells. The Jurkat cells produced both viruses at least 10 times more efficiently then the original cell lines; the pelleted virus from Jurkat cells was also less contaminated with non-virion proteins. Accordingly, a higher specificity was attained in an ELISA for antibodies to HTLV-III if the antigenic activity was derived from the virus from Jurkat cells, as opposed to that from H9 cells.
References
- Int J Cancer. 1978 Aug 15;22(2):204-13 - PubMed
- Nature. 1970 Aug 15;227(5259):680-5 - PubMed
- Science. 1984 Aug 24;225(4664):840-2 - PubMed
- Med Microbiol Immunol. 1985;174(1):35-42 - PubMed
- Science. 1984 May 4;224(4648):500-3 - PubMed
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources