A review of toxicity from topical salicylic acid preparations - PubMed (original) (raw)
Review
. 2014 Apr;70(4):788-792.
doi: 10.1016/j.jaad.2013.12.005. Epub 2014 Jan 25.
Affiliations
- PMID: 24472429
- DOI: 10.1016/j.jaad.2013.12.005
Review
A review of toxicity from topical salicylic acid preparations
Raman K Madan et al. J Am Acad Dermatol. 2014 Apr.
Abstract
Topical salicylic acid is often used in dermatologic conditions because of its keratolytic, bacteriostatic, fungicidal, and photoprotective properties. The bioavailability of salicylic acid differs depending on the vehicle used and pH of transcellular fluids. Although rare, salicylic acid toxicity (salicylism) can occur from topical application. Physicians should be mindful of the potential for salicylism or even death from topically applied salicylic acid.
Keywords: ichthyosis; psoriasis; salicylic acid; salicylism; skin absorption; topical; toxicity.
Copyright © 2013 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.
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