Bacterial transformation: distribution, shared mechanisms and divergent control - PubMed (original) (raw)

Review

doi: 10.1038/nrmicro3199. Epub 2014 Feb 10.

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• PMID: 24509783
• DOI: 10.1038/nrmicro3199

Review

Bacterial transformation: distribution, shared mechanisms and divergent control

Calum Johnston et al. Nat Rev Microbiol. 2014 Mar.

Abstract

Natural bacterial transformation involves the internalization and chromosomal integration of DNA and has now been documented in ~80 species. Recent advances have established that phylogenetically distant species share conserved uptake and processing proteins but differ in the inducing cues and regulatory mechanisms that are involved. In this Review, we highlight divergent and common principles that govern the transformation process in different bacteria. We discuss how this cumulative knowledge enables the prediction of new transformable species and supports the idea that the main role of internalized DNA is in the generation of genetic diversity or in chromosome repair rather than in nutrition.

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References

1. 1. Mol Microbiol. 2013 Mar;87(6):1113-32 - PubMed
2. 1. Mol Microbiol. 2012 Oct;86(2):241-5 - PubMed
3. 1. Curr Opin Microbiol. 2012 Oct;15(5):570-6 - PubMed
4. 1. Mol Microbiol. 2001 Jul;41(2):379-91 - PubMed
5. 1. Nature. 2002 Jan 31;415(6871):545-9 - PubMed

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