Effects of lipid-lowering agents on inflammation, haemostasis and blood pressure - PubMed (original) (raw)
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Effects of lipid-lowering agents on inflammation, haemostasis and blood pressure
Konstantinos Tziomalos et al. Curr Pharm Des. 2014.
Abstract
In addition to the modification of the lipid profile, most lipid-lowering agents appear to modulate other atherogenic pathways. We summarize the effects of lipid-lowering agents on inflammation, hemostasis and blood pressure. We also discuss the potential contribution of these actions on cardiovascular disease prevention. Most lipid-lowering agents appear to exert anti-inflammatory, antithrombotic and antihypertensive effects. These pleiotropic actions appear to contribute to the reduction in cardiovascular events and deep venous thrombosis during statin treatment. Regarding other lipid-lowering agents, it is unclear whether their effects on inflammation, thrombosis or blood pressure play a role in their antiatherogenic potential.
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