Improving the adherence of type 2 diabetes mellitus patients with pharmacy care: a systematic review of randomized controlled trials - PubMed (original) (raw)

Improving the adherence of type 2 diabetes mellitus patients with pharmacy care: a systematic review of randomized controlled trials

Sunya-Lee Antoine et al. BMC Endocr Disord. 2014.

Abstract

Background: Oral medication for patients with type 2 diabetes mellitus plays an important role in diabetes care and is associated with a high level self-care behavior and self-management. However, poor adherence to diabetes treatment is common which causes severe health complications and increased mortality. Barriers to adherence may consist of complex treatment regimens often along with long-term multi-therapies, side effects due to the medication as well as insufficient, incomprehensible or confusing information or instructions provided by the health care provider. Multidisciplinary approaches can support adherence success and can enable a more effective management of diabetes care. One approach in diabetes care can be the involvement of a pharmacist. The aim was to analyze the effectiveness of adherence-enhancing pharmacist interventions for oral medication in type 2 diabetes mellitus.

Methods: A systematic review of randomized controlled trials. The study quality was assessed with the Cochrane risk of bias tool.

Results: Of 491 hits, six publications were included. Two studies mainly examining educational interventions showed a significant improvement in adherence. Moreover, the quality of the included studies was deficient.

Conclusion: Although pharmacist interventions might potentially improve adherence to type 2 diabetes mellitus medication, high-quality studies are needed to assess effectiveness.

PubMed Disclaimer

Figures

Figure 1

Figure 1

Flow diagram of study selection.

References

    1. World Health Organisation (WHO) Adherence to Long-Term Therapies-Evidence for action. 2003.
    1. Cramer JA, Okikawa J, Bellaire S, Clauson P. Compliance with inhaled insulin treatment using the AERx(registered trademark) iDMS insulin diabetes management system. Diab Technol Ther. 2004;6(6):800–807. - PubMed
    1. Vermeire EIJJ, Wens J, Van Royen P, Biot Y, Hearnshaw H, Lindenmeyer A. Interventions for improving adherence to treatment recommendations in people with type 2 diabetes mellitus. Cochrane Database Syst Rev. 2005. p. CD003638. - PMC - PubMed
    1. Ho PM, Rumsfeld JS, Masoudi FA, McClure DL, Plomondon ME, Steiner JF, Magid DJ. Effect of medication nonadherence on hospitalization and mortality among patients with diabetes mellitus. Arch Intern Med. 2006;166(17):1836–1841. PubMed PMID: 17000939. Epub 2006/09/27. eng. - PubMed
    1. Currie CJ, Peyrot M, Morgan CL, Poole CD, Jenkins-Jones S, Rubin RR, Burton CM, Evans M. The impact of treatment noncompliance on mortality in people with type 2 diabetes. Diabetes Care. 2012;35(6):1279–1284. PubMed PMID: 22511257. Pubmed Central PMCID: 3357221. Epub 2012/04/19. eng. - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources