Association between exposure to hepatitis B virus and chronic kidney disease in China - PubMed (original) (raw)

. 2014 Oct;42(5):1178-84.

doi: 10.1177/0300060514541828.

Affiliations

Free article

Association between exposure to hepatitis B virus and chronic kidney disease in China

Qiang Zeng et al. J Int Med Res. 2014 Oct.

Free article

Abstract

Objective: Hospital-based, cross-sectional study to determine whether exposure to hepatitis B virus (HBV) has an independent effect on the risk of developing chronic kidney disease (CKD).

Methods: Han Chinese adults undergoing routine physical examinations were recruited. Blood was tested for the presence of hepatitis C virus (HCV) antibodies, HBV surface antigen, and antibodies against HBV core antigen and hepatitis B surface antigen (HBsAg). CKD was defined as estimated glomerular filtration rate (eGFR) <60 ml/min per 1.73 m(2) or presence of albuminuria.

Results: The prevalence of HBV exposure was 42.1% (6,418/15,259 participants). There were no significant associations between HBV or HCV status and CKD, low eGFR or albuminuria.

Conclusion: There was no association between exposure to HBV and the risk of developing CKD in this Chinese study population.

Keywords: CKD; HCV; Past exposure to HBV; chronic HBV carrier.

© The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

PubMed Disclaimer

Publication types

MeSH terms

Substances

LinkOut - more resources