Statistical analysis of mammalian pre-mRNA splicing sites - PubMed (original) (raw)

Statistical analysis of mammalian pre-mRNA splicing sites

M S Gelfand. Nucleic Acids Res. 1989.

Free PMC article

Abstract

222 donor and 222 acceptor (including 206 pairs) non-homologous splicing sites were studied. Well known features of these were confirmed and some novel observations were made. It is (1) cCAGGGag signal in (-60)-(-58) region of acceptor sites; (2) strong complementarity between regions (-69)-(-55) and (-36)-(-22) of some of the acceptor sites, and (3) small but statistically significant correlation between discrimination energies of corresponding donor and acceptor sites.

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