Physical influences of the extracellular environment on cell migration - PubMed (original) (raw)
Review
. 2014 Dec;15(12):813-24.
doi: 10.1038/nrm3897. Epub 2014 Oct 30.
Affiliations
- PMID: 25355506
- DOI: 10.1038/nrm3897
Review
Physical influences of the extracellular environment on cell migration
Guillaume Charras et al. Nat Rev Mol Cell Biol. 2014 Dec.
Abstract
The way in which a cell migrates is influenced by the physical properties of its surroundings, in particular the properties of the extracellular matrix. How the physical aspects of the cell's environment affect cell migration poses a considerable challenge when trying to understand migration in complex tissue environments and hinders the extrapolation of in vitro analyses to in vivo situations. A comprehensive understanding of these problems requires an integrated biochemical and biophysical approach. In this Review, we outline the findings that have emerged from approaches that span these disciplines, with a focus on actin-based cell migration in environments with different stiffness, dimensionality and geometry.
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References
- Nature. 2013 May 23;497(7450):507-11 - PubMed
- Integr Biol (Camb). 2009 Sep;1(8-9):506-12 - PubMed
- Biomaterials. 2009 Oct;30(29):5433-44 - PubMed
- Cell. 2009 Nov 25;139(5):891-906 - PubMed
- Nat Cell Biol. 2004 Oct;6(10):977-83 - PubMed
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