MERS coronavirus neutralizing antibodies in camels, Eastern Africa, 1983-1997 - PubMed (original) (raw)

. 2014 Dec;20(12):2093-5.

doi: 10.3201/eid2012.141026.

Victor Max Corman, Joerg Jores, Benjamin Meyer, Mario Younan, Anne Liljander, Berend-Jan Bosch, Erik Lattwein, Mosaad Hilali, Bakri E Musa, Set Bornstein, Christian Drosten

• PMID: 25425139
• PMCID: PMC4257824
• DOI: 10.3201/eid2012.141026

MERS coronavirus neutralizing antibodies in camels, Eastern Africa, 1983-1997

Marcel A Müller et al. Emerg Infect Dis. 2014 Dec.

Abstract

To analyze the distribution of Middle East respiratory syndrome coronavirus (MERS-CoV)-seropositive dromedary camels in eastern Africa, we tested 189 archived serum samples accumulated during the past 30 years. We identified MERS-CoV neutralizing antibodies in 81.0% of samples from the main camel-exporting countries, Sudan and Somalia, suggesting long-term virus circulation in these animals.

PubMed Disclaimer

Figures

Figure

Arabian Peninsula and neighboring countries of the Greater Horn of Africa in 2014. The study sites Egypt, Sudan (separated into Sudan and South Sudan), and Somalia are in dark orange and labeled with the year the camels were sampled, the number of samples, and the percentage of samples that were reactive in the MERS-CoV ELISA. Countries with previously reported MERS-CoV seropositive dromedaries are in light orange (overlap shown in stripes).

Similar articles

• The prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) antibodies in dromedary camels in Israel.
  Harcourt JL, Rudoler N, Tamin A, Leshem E, Rasis M, Giladi M, Haynes LM. Harcourt JL, et al. Zoonoses Public Health. 2018 Sep;65(6):749-754. doi: 10.1111/zph.12482. Epub 2018 May 31. Zoonoses Public Health. 2018. PMID: 29855166 Free PMC article.
• MERS-CoV in Camels but Not Camel Handlers, Sudan, 2015 and 2017.
  Farag E, Sikkema RS, Mohamedani AA, de Bruin E, Munnink BBO, Chandler F, Kohl R, van der Linden A, Okba NMA, Haagmans BL, van den Brand JMA, Elhaj AM, Abakar AD, Nour BYM, Mohamed AM, Alwaseela BE, Ahmed H, Alhajri MM, Koopmans M, Reusken C, Elrahman SHA. Farag E, et al. Emerg Infect Dis. 2019 Dec;25(12):2333-2335. doi: 10.3201/eid2512.190882. Emerg Infect Dis. 2019. PMID: 31742534 Free PMC article.
• Antibodies against MERS coronavirus in dromedary camels, United Arab Emirates, 2003 and 2013.
  Meyer B, Müller MA, Corman VM, Reusken CB, Ritz D, Godeke GJ, Lattwein E, Kallies S, Siemens A, van Beek J, Drexler JF, Muth D, Bosch BJ, Wernery U, Koopmans MP, Wernery R, Drosten C. Meyer B, et al. Emerg Infect Dis. 2014 Apr;20(4):552-9. doi: 10.3201/eid2004.131746. Emerg Infect Dis. 2014. PMID: 24655412 Free PMC article.
• Middle East respiratory syndrome coronavirus (MERS-CoV): animal to human interaction.
  Omrani AS, Al-Tawfiq JA, Memish ZA. Omrani AS, et al. Pathog Glob Health. 2015;109(8):354-62. doi: 10.1080/20477724.2015.1122852. Pathog Glob Health. 2015. PMID: 26924345 Free PMC article. Review.
• Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir.
  Mohd HA, Al-Tawfiq JA, Memish ZA. Mohd HA, et al. Virol J. 2016 Jun 3;13:87. doi: 10.1186/s12985-016-0544-0. Virol J. 2016. PMID: 27255185 Free PMC article. Review.

Cited by

• Biphasic MERS-CoV Incidence in Nomadic Dromedaries with Putative Transmission to Humans, Kenya, 2022-2023.
  Ogoti BM, Riitho V, Wildemann J, Mutono N, Tesch J, Rodon J, Harichandran K, Emanuel J, Möncke-Buchner E, Kiambi S, Oyugi J, Mureithi M, Corman VM, Drosten C, Thumbi SM, Müller MA. Ogoti BM, et al. Emerg Infect Dis. 2024 Mar;30(3):581-585. doi: 10.3201/eid3003.231488. Emerg Infect Dis. 2024. PMID: 38407189 Free PMC article.
• The coevolutionary mosaic of bat betacoronavirus emergence risk.
  Forero-Muñoz NR, Muylaert RL, Seifert SN, Albery GF, Becker DJ, Carlson CJ, Poisot T. Forero-Muñoz NR, et al. Virus Evol. 2023 Dec 20;10(1):vead079. doi: 10.1093/ve/vead079. eCollection 2024. Virus Evol. 2023. PMID: 38361817 Free PMC article.
• Zoonoses research in Somalia: A scoping review using a One Health approach.
  Mumin FI, Fenton A, Osman AY, Mor SM. Mumin FI, et al. One Health. 2023 Sep 1;17:100626. doi: 10.1016/j.onehlt.2023.100626. eCollection 2023 Dec. One Health. 2023. PMID: 38024257 Free PMC article. Review.
• Rapid response screening for emerging zoonotic pathogens, barriers and opportunities: A study for enhanced preparedness of the Netherlands.
  Streng K, de Best PA, Timen A, Koopmans MPG, van der Poel WHM, Sikkema RS. Streng K, et al. One Health. 2023 Feb 14;16:100507. doi: 10.1016/j.onehlt.2023.100507. eCollection 2023 Jun. One Health. 2023. PMID: 36852195 Free PMC article.
• Single Amino Acid Substitution in the Receptor Binding Domain of Spike Protein Is Sufficient To Convert the Neutralization Profile between Ethiopian and Middle Eastern Isolates of Middle East Respiratory Coronavirus.
  Sugimoto S, Kakizaki M, Kawase M, Kawachi K, Ujike M, Kamitani W, Sentsui H, Shirato K. Sugimoto S, et al. Microbiol Spectr. 2023 Feb 6;11(2):e0459022. doi: 10.1128/spectrum.04590-22. Online ahead of print. Microbiol Spectr. 2023. PMID: 36744940 Free PMC article.

References

1. 1. Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med. 2012;367:1814–20 . 10.1056/NEJMoa1211721 - DOI - PubMed
2. 1. European Centre for Disease Prevention and Control. Epidemiological update: Middle East respiratory syndrome coronavirus (MERS-CoV). 02 July 2014. [cited 2014 Jul 3]. http://www.ecdc.europa.eu/en/press/news/_layouts/forms/News_DispForm.asp...
3. 1. Corman VM, Jores J, Meyer B, Younan M, Liljander A, Said MY, et al. Antibodies against MERS coronavirus in dromedary camels, Kenya, 1992–2013. Emerg Infect Dis [Internet]. 2014. Aug [cited 2014 Jul 21]. 10.3201/eid2008.140596 - DOI - PMC - PubMed
4. 1. Hemida M, Perera R, Al Jassim R, Kayali G, Siu L, Wang P, et al. Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity. Euro Surveill. 2014;19:20828 . - PMC - PubMed
5. 1. Hemida MG, Chu DK, Poon LL, Perera RA, Alhammadi MA, Ng HY, et al. MERS coronavirus in dromedary camel herd, Saudi Arabia. Emerg Infect Dis. 2014;20:••• . 10.3201/eid2007.140571 - DOI - PMC - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • CDC-NCEZID
  • Europe PubMed Central
  • PubMed Central

• Other Literature Sources

  • H1 Connect
  • The Lens - Patent Citations
  • scite Smart Citations

• Miscellaneous

  • NCI CPTAC Assay Portal