Definition of an Ets1 protein domain required for nuclear localization in cells and DNA-binding activity in vitro - PubMed (original) (raw)

Comparative Study

Definition of an Ets1 protein domain required for nuclear localization in cells and DNA-binding activity in vitro

K E Boulukos et al. Mol Cell Biol. 1989 Dec.

Abstract

Ets1 and Ets2 are nuclear phosphoproteins which bind to DNA in vitro and share two domains of strong identity. Deletion analyses of each of these conserved regions in Ets1 demonstrated that integrity of the carboxy-terminal domain, also conserved in the more distantly related elk and erg gene products, is essential for both nuclear targeting and DNA-binding activity in vitro.

PubMed Disclaimer

References

    1. Nucleic Acids Res. 1983 Oct 25;11(20):7119-36 - PubMed
    1. Proc Natl Acad Sci U S A. 1987 May;84(10):3161-5 - PubMed
    1. Cell. 1986 Jan 17;44(1):77-85 - PubMed
    1. Proc Natl Acad Sci U S A. 1986 Mar;83(6):1714-8 - PubMed
    1. Mol Cell Biol. 1985 Nov;5(11):2993-3000 - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources