Collaborative computational project for electron cryo-microscopy - PubMed (original) (raw)

Collaborative computational project for electron cryo-microscopy

Chris Wood et al. Acta Crystallogr D Biol Crystallogr. 2015.

Abstract

The Collaborative Computational Project for Electron cryo-Microscopy (CCP-EM) has recently been established. The aims of the project are threefold: to build a coherent cryoEM community which will provide support for individual scientists and will act as a focal point for liaising with other communities, to support practising scientists in their use of cryoEM software and finally to support software developers in producing and disseminating robust and user-friendly programs. The project is closely modelled on CCP4 for macromolecular crystallography, and areas of common interest such as model fitting, underlying software libraries and tools for building program packages are being exploited. Nevertheless, cryoEM includes a number of techniques covering a large range of resolutions and a distinct project is required. In this article, progress so far is reported and future plans are discussed.

Keywords: CCP-EM; Collaborative Computational Project for Electron cryo-Microscopy.

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Figures

Figure 1

Figure 1

Overview of CCP-EM activities. The green sector refers to community-building activities, and is represented by a map of current groups performing high-resolution cryoEM. The blue sector refers to user-support activities, which are illustrated by the CCP-EM GUI currently under development and a snapshot of the CCP-EM website. Finally, the red sector refers to support of software developers, and is illustrated by the front page of CCPForge, which hosts the CCP-EM software project, and a schematic of the developing CCP-EM library.

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