Reduction of phytic acid and enhancement of bioavailable micronutrients in food grains - PubMed (original) (raw)

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Reduction of phytic acid and enhancement of bioavailable micronutrients in food grains

Raj Kishor Gupta et al. J Food Sci Technol. 2015 Feb.

Abstract

More than half of the world populations are affected by micronutrient malnutrition and one third of world's population suffers from anemia and zinc deficiency, particularly in developing countries. Iron and zinc deficiencies are the major health problems worldwide. Phytic acid is the major storage form of phosphorous in cereals, legumes, oil seeds and nuts. Phytic acid is known as a food inhibitor which chelates micronutrient and prevents it to be bioavailabe for monogastric animals, including humans, because they lack enzyme phytase in their digestive tract. Several methods have been developed to reduce the phytic acid content in food and improve the nutritional value of cereal which becomes poor due to such antinutrient. These include genetic improvement as well as several pre-treatment methods such as fermentation, soaking, germination and enzymatic treatment of grains with phytase enzyme. Biofortification of staple crops using modern biotechnological techniques can potentially help in alleviating malnutrition in developing countries.

Keywords: Dephytinization; Micronutrients; Monogastric animals; Phytase; Phytic acid.

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Figures

Fig. 1

Fig. 1

The phytic acid biosynthetic pathway in plants where A, B, C, D and E are the genes involved in phytic acid biosynthesis pathway. A.MIPS(myo-inositol 3-phosphate synthase) B. IMP(inositol monophosphatase) C. IPK2(inositol1,4,5-tris phosphate kinase) D. IPK1(inositol 1,3,4,5,6-pentakis phosphate 2-kinase) E. ITP5/6 K(inositol 1,3,4-trisphophate 5/6-kinase). G6P:glucose 6-phosphate, Ins:myo-inositol, PtdIns:phophatidyl inositol (Suzuki et al. 2007)

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References

    1. Agte VV, Gokhale MK, Chiplonkar SA. Effect of natural fermentation on in vitro zinc bioavailability in cereal-legume mixture. Int J Food Sci Tech. 1997;31:29–32. doi: 10.1046/j.1365-2621.1997.00372.x. - DOI
    1. Ames BN (1966) Assay of inorganic phosphate, total phosphate and phosphatases. Methods Enzymol 8:115–118
    1. Asada K, Tanaka K, Kasai Z. Formation of phytic acid in cereal grains. Ann NY Acad Sci. 1969;165:801–814. - PubMed
    1. Boesch DF, Brinsfield RB, Magnien RE. Chesapeake bay eutrophication: scientific understanding, ecosystem restoration, and challenges for agriculture. J Environ Qua. 2001;30:303–320. doi: 10.2134/jeq2001.302303x. - DOI - PubMed
    1. Bohn T, Davidsson L, Walczyk T, Hurrell RF. Phytic acid added to white-wheat bread inhibits fractional apparent magnesium absorption in humans. Am J Clin Nutr. 2004;79:418–423. - PubMed

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