Adult neurogenesis: a substrate for experience-dependent change - PubMed (original) (raw)
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Adult neurogenesis: a substrate for experience-dependent change
Maya Opendak et al. Trends Cogn Sci. 2015 Mar.
Abstract
A rapidly growing body of literature indicates that adult neurogenesis in the hippocampus is sensitive to a variety of environmental factors. The effects of emotionally salient experiences, such as stress and physical exercise, have been characterized extensively with regard to both adult neurogenesis and behaviors associated with the hippocampus. Experience-dependent changes in the production and function of new neurons may serve as a means to fine-tune the hippocampus to the predicted environment. Here, we discuss this possibility along with the argument that more naturalistic experimental conditions may be a necessary step toward understanding the adaptive significance of neurons born in the adult brain.
Keywords: adaptation; adult neurogenesis; anxiety; cognition; dentate gyrus.
Copyright © 2015 Elsevier Ltd. All rights reserved.
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