Porocarcinoma with perineural invasion - PubMed (original) (raw)
Case Reports
Porocarcinoma with perineural invasion
Ciara A Maguire et al. Indian Dermatol Online J. 2015 Mar-Apr.
Abstract
Herein we present the case of a 58 year old woman with porocarcinoma of the left forehead with perineural invasion, diagnosed after recurrence of previously excised benign poroma. This case serves as a reminder of the potential of malignant degeneration within long-standing benign adnexal tumors as well as the spectrum of histological features that may be seen in porocarcinoma.
Keywords: Perineural invasion; porocarcinoma; sweat gland neoplasm.
Conflict of interest statement
Conflict of Interest: None declared.
Figures
Figure 1
(a) Patient during her first presentation, bluish papule on the forehead approximately 6 mm in diameter, (b) Recurrence of the lesion as a much larger nodule in June 2012
Figure 2
Small, well-circumscribed, slightly eroded adnexal neoplasm connected with the epidermis. H and E, ×40
Figure 3
Neoplasm consisting of poroid and cuticular cells, with ductal differentiation. H and E, ×200
Figure 4
Ductal cells, some with abundant pink cytoplasm. H and E, ×400
Figure 5
Mostly circumscribed epithelial proliferation with ductal differentiation. H and E, ×40
Figure 6
Irregular focus with separate islands of cellular proliferation. H and E, ×40
Figure 7
Separated islands of cellular proliferation with similar ductal differentiation. H and E, ×200
Figure 8
Cells of the proliferation with abundant pink cytoplasm and nuclear atypia and numerous mitotic figures. H and E, ×200
Figure 9
Perineural invasion by atypical cells with abundant pink cytoplasm. H and E, ×400
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