Who determines the outcomes of HBV exposure? - PubMed (original) (raw)
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Who determines the outcomes of HBV exposure?
Baohong Wang et al. Trends Microbiol. 2015 Jun.
Abstract
Until recently, the reason for age-dependent immune clearance of hepatitis B virus remained elusive. A new study has revealed that establishment of the commensal gut microbiota could modulate the liver immunity phenotype in a hydrodynamic transfection mouse model, suggesting that natural gut-liver interactions can help achieve rapid viral clearance.
Keywords: HBV; age; gut microbiota; immunity.
Copyright © 2015. Published by Elsevier Ltd.
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- Age-related immune clearance of hepatitis B virus infection requires the establishment of gut microbiota.
Chou HH, Chien WH, Wu LL, Cheng CH, Chung CH, Horng JH, Ni YH, Tseng HT, Wu D, Lu X, Wang HY, Chen PJ, Chen DS. Chou HH, et al. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2175-80. doi: 10.1073/pnas.1424775112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646429 Free PMC article.
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