The renaissance of developmental biology - PubMed (original) (raw)

The renaissance of developmental biology

Daniel St Johnston. PLoS Biol. 2015.

Abstract

Since its heyday in the 1980s and 90s, the field of developmental biology has gone into decline; in part because it has been eclipsed by the rise of genomics and stem cell biology, and in part because it has seemed less pertinent in an era with so much focus on translational impact. In this essay, I argue that recent progress in genome-wide analyses and stem cell research, coupled with technological advances in imaging and genome editing, have created the conditions for the renaissance of a new wave of developmental biology with greater translational relevance.

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Conflict of interest statement

The author has declared that no competing interests exist.

Figures

Fig 1

Fig 1. An intestinal organoid grown from Lgr5+ stem cells (courtesy of Meritxell Huch).

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