Survival of Borrelia burgdorferi in antibiotically treated patients with Lyme borreliosis - PubMed (original) (raw)

Case Reports

. 1989 Nov-Dec;17(6):355-9.

doi: 10.1007/BF01645543.

Affiliations

Case Reports

Survival of Borrelia burgdorferi in antibiotically treated patients with Lyme borreliosis

V Preac-Mursic et al. Infection. 1989 Nov-Dec.

Abstract

The persistence of Borrelia burgdorferi in patients treated with antibiotics is described. The diagnosis of Lyme disease is based on clinical symptoms, epidemiology and specific IgG and IgM antibody titers to B. burgdorferi in serum. Antibiotic therapy may abrogate the antibody response to the infection as shown in our patients. B. burgdorferi may persist as shown by positive culture in MKP-medium; patients may have subclinical or clinical disease without diagnostic antibody titers to B. burgdorferi. We conclude that early stage of the disease as well as chronic Lyme disease with persistence of B. burgdorferi after antibiotic therapy cannot be excluded when the serum is negative for antibodies against B. burgdorferi.

PubMed Disclaimer

References

    1. Ann Intern Med. 1983 Jul;99(1):22-6 -PubMed
    1. Infection. 1984 Sep-Oct;12(5):331-7 -PubMed
    1. Arthritis Rheum. 1987 Apr;30(4):448-50 -PubMed
    1. Arthritis Rheum. 1987 Jun;30(6):705-8 -PubMed
    1. Ann N Y Acad Sci. 1988;539:324-45 -PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources