Incidence rate of type 2 diabetes is >50% lower in GrassrootsHealth cohort with median serum 25-hydroxyvitamin D of 41 ng/ml than in NHANES cohort with median of 22 ng/ml - PubMed (original) (raw)
. 2016 Jan;155(Pt B):239-44.
doi: 10.1016/j.jsbmb.2015.06.013. Epub 2015 Jul 4.
Affiliations
- PMID: 26151742
- DOI: 10.1016/j.jsbmb.2015.06.013
Free article
Incidence rate of type 2 diabetes is >50% lower in GrassrootsHealth cohort with median serum 25-hydroxyvitamin D of 41 ng/ml than in NHANES cohort with median of 22 ng/ml
S L McDonnell et al. J Steroid Biochem Mol Biol. 2016 Jan.
Free article
Abstract
Higher serum 25-hydroxyvitamin D [25(OH)D] concentrations have been associated with lower risk of type 2 diabetes. This study compared incidence rates of type 2 diabetes among participants aged ≥20 years in two U.S. cohorts with markedly different median 25(OH)D concentrations. The median 25(OH)D concentration in the GrassrootsHealth (GRH) cohort was 41 ng/ml (N=4933) while in the 2005-6 National Health and Nutrition Examination Survey (NHANES) it was 22 ng/ml (N=4078) (P<0.0001). The adjusted annual incidence rate of type 2 diabetes was 3.7 per 1000 population (95% confidence interval=1.9, 6.6) in the GRH cohort, compared to 9.3 per 1000 population (95% confidence interval=6.7, 12.6) in NHANES. In the NHANES cohort, the lowest 25(OH)D tertiles (<17, 17-24 ng/ml) had higher odds of developing diabetes than the highest tertile (OR: 4.9, P=0.02 and 4.8, P=0.01 respectively), adjusting for covariates. Differences in demographics and methods may have limited comparability. Raising serum 25(OH)D may be a useful tool for reducing risk of diabetes in the population.
Keywords: Serum 25–hydroxyvitamin D; Type 2 diabetes; Vitamin D.
Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.
Similar articles
- Low serum 25-hydroxyvitamin D is associated with increased risk of the development of the metabolic syndrome at five years: results from a national, population-based prospective study (The Australian Diabetes, Obesity and Lifestyle Study: AusDiab).
Gagnon C, Lu ZX, Magliano DJ, Dunstan DW, Shaw JE, Zimmet PZ, Sikaris K, Ebeling PR, Daly RM. Gagnon C, et al. J Clin Endocrinol Metab. 2012 Jun;97(6):1953-61. doi: 10.1210/jc.2011-3187. Epub 2012 Mar 22. J Clin Endocrinol Metab. 2012. PMID: 22442263 - Vitamin D status and community-acquired pneumonia: results from the third National Health and Nutrition Examination Survey.
Quraishi SA, Bittner EA, Christopher KB, Camargo CA Jr. Quraishi SA, et al. PLoS One. 2013 Nov 15;8(11):e81120. doi: 10.1371/journal.pone.0081120. eCollection 2013. PLoS One. 2013. PMID: 24260547 Free PMC article. - Association Between Serum 25-Hydroxyvitamin D Level and Human Papillomavirus Cervicovaginal Infection in Women in the United States.
Shim J, Pérez A, Symanski E, Nyitray AG. Shim J, et al. J Infect Dis. 2016 Jun 15;213(12):1886-92. doi: 10.1093/infdis/jiw065. Epub 2016 Feb 15. J Infect Dis. 2016. PMID: 26908722 - 25-Hydroxyvitamin D Status and Risk for Colorectal Cancer and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Epidemiological Studies.
Ekmekcioglu C, Haluza D, Kundi M. Ekmekcioglu C, et al. Int J Environ Res Public Health. 2017 Jan 28;14(2):127. doi: 10.3390/ijerph14020127. Int J Environ Res Public Health. 2017. PMID: 28134804 Free PMC article. Review. - Low vitamin D levels increase the risk of type 2 diabetes in older adults: A systematic review and meta-analysis.
Lucato P, Solmi M, Maggi S, Bertocco A, Bano G, Trevisan C, Manzato E, Sergi G, Schofield P, Kouidrat Y, Veronese N, Stubbs B. Lucato P, et al. Maturitas. 2017 Jun;100:8-15. doi: 10.1016/j.maturitas.2017.02.016. Epub 2017 Mar 21. Maturitas. 2017. PMID: 28539181 Review.
Cited by
- Exposure to a Vitamin D Best Practices Toolkit, Model, and E-Tools Increases Knowledge, Confidence, and the Translation of Research to Public Health and Practice.
Sanford BS, Aliano JL, Omary CS, McDonnell SL, Kimball SM, Grant WB. Sanford BS, et al. Nutrients. 2023 May 24;15(11):2446. doi: 10.3390/nu15112446. Nutrients. 2023. PMID: 37299409 Free PMC article. - Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths.
Grant WB, Lahore H, McDonnell SL, Baggerly CA, French CB, Aliano JL, Bhattoa HP. Grant WB, et al. Nutrients. 2020 Apr 2;12(4):988. doi: 10.3390/nu12040988. Nutrients. 2020. PMID: 32252338 Free PMC article. Review. - Systematic Review on Vitamin D Level in Apparently Healthy Indian Population and Analysis of Its Associated Factors.
Selvarajan S, Gunaseelan V, Anandabaskar N, Xavier AS, Srinivasamurthy S, Kamalanathan SK, Sahoo JP. Selvarajan S, et al. Indian J Endocrinol Metab. 2017 Sep-Oct;21(5):765-775. doi: 10.4103/ijem.IJEM_168_17. Indian J Endocrinol Metab. 2017. PMID: 28989890 Free PMC article. Review. - Low glycemic index diet, exercise and vitamin D to reduce breast cancer recurrence (DEDiCa): design of a clinical trial.
Augustin LS, Libra M, Crispo A, Grimaldi M, De Laurentiis M, Rinaldo M, D'Aiuto M, Catalano F, Banna G, Ferrau' F, Rossello R, Serraino D, Bidoli E, Massarut S, Thomas G, Gatti D, Cavalcanti E, Pinto M, Riccardi G, Vidgen E, Kendall CW, Jenkins DJ, Ciliberto G, Montella M. Augustin LS, et al. BMC Cancer. 2017 Jan 23;17(1):69. doi: 10.1186/s12885-017-3064-4. BMC Cancer. 2017. PMID: 28114909 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical