Relevance of dietary glycerophospholipids and sphingolipids to human health - PubMed (original) (raw)

Review

Relevance of dietary glycerophospholipids and sphingolipids to human health

P Castro-Gómez et al. Prostaglandins Leukot Essent Fatty Acids. 2015 Oct.

Abstract

Glycerophospholipids and sphingolipids participate in a variety of indispensable metabolic, neurological, and intracellular signaling processes. In this didactic paper we review the biological roles of phospholipids and try to unravel the precise nature of their putative healthful activities. We conclude that the biological actions of phospholipids activities potentially be nutraceutically exploited in the adjunct therapy of widely diffused pathologies such as neurodegeneration or the metabolic syndrome. As phospholipids can be recovered from inexpensive sources such as food processing by-products, ad-hoc investigation is warranted.

Keywords: Atherosclerosis; Milk fat globule membranes; Phosphatidylcholine; Phospholipids; Sphingolipids; Sphingosine.

PubMed Disclaimer

Cited by

The Role of Food Matrices Supplemented with Milk Fat Globule Membrane in the Bioaccessibility of Lipid Components and Adaptation of Cellular Lipid Metabolism of Caco-2 Cells.
Martínez-Sánchez V, Calvo MV, Fontecha J, Pérez-Gálvez A. Martínez-Sánchez V, et al. Nutrients. 2024 Aug 22;16(16):2798. doi: 10.3390/nu16162798. Nutrients. 2024. PMID: 39203935 Free PMC article.
Lipidomic profiling of patient-specific iPSC-derived hepatocyte-like cells.
Kiamehr M, Viiri LE, Vihervaara T, Koistinen KM, Hilvo M, Ekroos K, Käkelä R, Aalto-Setälä K. Kiamehr M, et al. Dis Model Mech. 2017 Sep 1;10(9):1141-1153. doi: 10.1242/dmm.030841. Epub 2017 Jul 21. Dis Model Mech. 2017. PMID: 28733363 Free PMC article.
The role of microbial metabolites in diabetic kidney disease.
Zhu T, Hu BY, Zhang YQ, Zhang ZY, Cai KW, Lei L, Hu B, Wang XH, Tang C, Lu YP, Zheng ZH. Zhu T, et al. Heliyon. 2023 Jul 4;9(7):e17844. doi: 10.1016/j.heliyon.2023.e17844. eCollection 2023 Jul. Heliyon. 2023. PMID: 37539130 Free PMC article.
Shotgun Metagenomics of Gut Microbiota in Humans with up to Extreme Longevity and the Increasing Role of Xenobiotic Degradation.
Rampelli S, Soverini M, D'Amico F, Barone M, Tavella T, Monti D, Capri M, Astolfi A, Brigidi P, Biagi E, Franceschi C, Turroni S, Candela M. Rampelli S, et al. mSystems. 2020 Mar 24;5(2):e00124-20. doi: 10.1128/mSystems.00124-20. mSystems. 2020. PMID: 32209716 Free PMC article.
Enhancing the Signal-to-Noise of Diagnostic Fragment Ions of Unsaturated Glycerophospholipids via Precursor Exclusion Ultraviolet Photodissociation Mass Spectrometry (PEx-UVPD-MS).
Shields SWJ, Sanders JD, Brodbelt JS. Shields SWJ, et al. Anal Chem. 2022 Aug 16;94(32):11352-11359. doi: 10.1021/acs.analchem.2c02128. Epub 2022 Aug 2. Anal Chem. 2022. PMID: 35917227 Free PMC article.

Relevance of dietary glycerophospholipids and sphingolipids to human health - PubMed (original) (raw)