Fusobacterium nucleatum Osteomyelitis in 3 Previously Healthy Children: A Case Series and Review of the Literature - PubMed (original) (raw)
Review
Fusobacterium nucleatum Osteomyelitis in 3 Previously Healthy Children: A Case Series and Review of the Literature
Seth W Gregory et al. J Pediatric Infect Dis Soc. 2015 Dec.
Abstract
Fusobacterium nucleatum is a rare cause of monomicrobial osteomyelitis in children. We describe the cases of 3 children with F. nucleatum osteomyelitis of the distal femoral epiphysis with concurrent septic arthritis and review 6 other cases reported in the literature. Our report emphasizes the importance of maintaining a high index of suspicion for anaerobic osteomyelitis, given its atypical presentation and the unique growth requirements of anaerobic bacteria.
Keywords: anaerobic osteomyelitis; epiphyseal lesion; pediatric.
© The Author 2015. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
Figures
Figure 1.
Sagittal SPGR post-contrast image (A) and T2 axial image (B) showing discrete lesion in the femoral notch in the posteromedial aspect of the knee. Diffuse edema was also noted throughout the notch and medial epiphysis. Repeat MRI after knee arthrotomy and 7 days of piperacillin-tazobactam shows worsening of the osteomyelitis and large joint effusion (C, D).
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