Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci - PubMed (original) (raw)

Comparative Study

. 2015 Dec;47(12):1415-25.

doi: 10.1038/ng.3437. Epub 2015 Nov 9.

Teresa Ferreira 1, Yeji Lee 3, Anne Raimondo 4, Reedik Mägi 5, Michael E Reschen 6, Anubha Mahajan 1, Adam Locke 3, N William Rayner 1 4 7, Neil Robertson 1 4, Robert A Scott 8, Inga Prokopenko 9, Laura J Scott 3, Todd Green 10, Thomas Sparso 11, Dorothee Thuillier 12, Loic Yengo 12, Harald Grallert 13 14 15, Simone Wahl 13 14 15, Mattias Frånberg 16 17 18, Rona J Strawbridge 16, Hans Kestler 19 20, Himanshu Chheda 21, Lewin Eisele 22, Stefan Gustafsson 23, Valgerdur Steinthorsdottir 24, Gudmar Thorleifsson 24, Lu Qi 25 26 27 28, Lennart C Karssen 29, Elisabeth M van Leeuwen 29, Sara M Willems 8 29, Man Li 30, Han Chen 31 32, Christian Fuchsberger 3, Phoenix Kwan 3, Clement Ma 3, Michael Linderman 33, Yingchang Lu 34, Soren K Thomsen 4, Jana K Rundle 4, Nicola L Beer 1 4, Martijn van de Bunt 1 4, Anil Chalisey 6, Hyun Min Kang 3, Benjamin F Voight 35, Gonçalo R Abecasis 3, Peter Almgren 36, Damiano Baldassarre 37 38, Beverley Balkau 39 40, Rafn Benediktsson 41 42, Matthias Blüher 43 44, Heiner Boeing 45, Lori L Bonnycastle 46, Erwin P Bottinger 47, Noël P Burtt 10, Jason Carey 10, Guillaume Charpentier 48, Peter S Chines 46, Marilyn C Cornelis 49, David J Couper 50, Andrew T Crenshaw 10, Rob M van Dam 26 51, Alex S F Doney 52 53, Mozhgan Dorkhan 54, Sarah Edkins 7, Johan G Eriksson 55 56 57 58, Tonu Esko 5 59 60, Elodie Eury 61, João Fadista 36, Jason Flannick 10, Pierre Fontanillas 10, Caroline Fox 62 63, Paul W Franks 26 36 64 65, Karl Gertow 16, Christian Gieger 13 14, Bruna Gigante 66, Omri Gottesman 47, George B Grant 10, Niels Grarup 11, Christopher J Groves 4, Maija Hassinen 67, Christian T Have 11, Christian Herder 68 69, Oddgeir L Holmen 70, Astradur B Hreidarsson 42, Steve E Humphries 71, David J Hunter 25 26 27 72, Anne U Jackson 3, Anna Jonsson 36, Marit E Jørgensen 73, Torben Jørgensen 74 75 76, Wen-Hong L Kao 30, Nicola D Kerrison 8, Leena Kinnunen 55, Norman Klopp 13 77, Augustine Kong 24, Peter Kovacs 43 44, Peter Kraft 25 32 72, Jasmina Kravic 36, Cordelia Langford 7, Karin Leander 66, Liming Liang 25 32, Peter Lichtner 78, Cecilia M Lindgren 1 10, Eero Lindholm 36, Allan Linneberg 74 79 80, Ching-Ti Liu 31, Stéphane Lobbens 61, Jian'an Luan 8, Valeriya Lyssenko 36 73, Satu Männistö 55, Olga McLeod 16, Julia Meyer 81, Evelin Mihailov 5, Ghazala Mirza 82, Thomas W Mühleisen 83 84 85, Martina Müller-Nurasyid 81 86 87 88, Carmen Navarro 89 90 91, Markus M Nöthen 83 84, Nikolay N Oskolkov 36, Katharine R Owen 4 92, Domenico Palli 93, Sonali Pechlivanis 22, Leena Peltonen 7 10 21 55, John R B Perry 8, Carl G P Platou 70 94, Michael Roden 68 69 95, Douglas Ruderfer 96, Denis Rybin 97, Yvonne T van der Schouw 98, Bengt Sennblad 16 17, Gunnar Sigurðsson 42 99, Alena Stančáková 100, Gerald Steinbach 101, Petter Storm 36, Konstantin Strauch 81 87, Heather M Stringham 3, Qi Sun 26 27, Barbara Thorand 14 15, Emmi Tikkanen 21 102, Anke Tonjes 43 44, Joseph Trakalo 1, Elena Tremoli 37 38, Tiinamaija Tuomi 21 58 103 104, Roman Wennauer 105, Steven Wiltshire 1, Andrew R Wood 106, Eleftheria Zeggini 7, Ian Dunham 107, Ewan Birney 107, Lorenzo Pasquali 108 109 110, Jorge Ferrer 111 112, Ruth J F Loos 8 34 47 113, Josée Dupuis 31 62, Jose C Florez 60 114 115 116, Eric Boerwinkle 117 118, James S Pankow 119, Cornelia van Duijn 29 120, Eric Sijbrands 105, James B Meigs 114 121, Frank B Hu 25 26 27, Unnur Thorsteinsdottir 24 41, Kari Stefansson 24 41, Timo A Lakka 67 122 123, Rainer Rauramaa 67 123, Michael Stumvoll 43 44, Nancy L Pedersen 124, Lars Lind 125, Sirkka M Keinanen-Kiukaanniemi 126 127, Eeva Korpi-Hyövälti 128, Timo E Saaristo 129 130, Juha Saltevo 131, Johanna Kuusisto 100, Markku Laakso 100, Andres Metspalu 5 132, Raimund Erbel 133, Karl-Heinz Jöcke 122, Susanne Moebus 22, Samuli Ripatti 7 21 102 134, Veikko Salomaa 55, Erik Ingelsson 1 23, Bernhard O Boehm 135 136, Richard N Bergman 137, Francis S Collins 46, Karen L Mohlke 138, Heikki Koistinen 55 139 140, Jaakko Tuomilehto 55 141 142 143, Kristian Hveem 70, Inger Njølstad 144, Panagiotis Deloukas 7 145, Peter J Donnelly 1 146, Timothy M Frayling 106, Andrew T Hattersley 147, Ulf de Faire 66, Anders Hamsten 16, Thomas Illig 13 77, Annette Peters 14 15 88, Stephane Cauchi 12, Rob Sladek 148 149, Philippe Froguel 9 12 61, Torben Hansen 11 150, Oluf Pedersen 11, Andrew D Morris 151, Collin N A Palmer 52 53, Sekar Kathiresan 10 115 152, Olle Melander 36, Peter M Nilsson 36, Leif C Groop 21 36, Inês Barroso 7 153 154, Claudia Langenberg 8, Nicholas J Wareham 8, Christopher A O'Callaghan 6, Anna L Gloyn 1 4 92, David Altshuler 10 114 115 116 155 156, Michael Boehnke 3, Tanya M Teslovich 3, Mark I McCarthy 1 4 92, Andrew P Morris 1 5 157 158; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium