Comparison of ginger with vitamin B6 in relieving nausea and vomiting during pregnancy - PubMed (original) (raw)
Comparison of ginger with vitamin B6 in relieving nausea and vomiting during pregnancy
Mozhgan Firouzbakht et al. Ayu. 2014 Jul-Sep.
Abstract
Background: Nausea and vomiting are the most common complicated issues in pregnancy period, but they have not been paid much attention. Herb based formulations can be effectively used for the treatment nausea and vomiting observed during pregnancy.
Aim: To investigate the effect of ginger in nausea and vomiting during pregnancy in comparison with vitamin B6 and placebo.
Materials and methods: This is a randomized and double-blind clinical trial. The women who had nausea and vomiting and did not take any medications were included in this study. 120 women were selected by simple random sampling method, and divided into three groups and were given vitamin B6, placebo, and ginger, respectively. 97 women completed the treatment. They were given treatment for 4 days and were followed after a week. The instrument used in this study was a questionnaire, including demographic characteristic and determining severity nausea and vomiting based on the analog visual scale. Data were analyzed with SPSS software and t-test and Kruskal-Wallis test.
Results: There was significant difference between groups in severity of nausea and frequency of vomiting (P < 0.001).
Conclusion: Ginger was effective in treating nausea and vomiting in pregnancy, but its use needs further studies to determine the proper dosage and the confirmation about the safety of this drug for a pregnant mother and her fetus.
Keywords: Ginger; nausea; placebo; pregnancy; vitamin B6; vomiting.
Conflict of interest statement
Conflict of Interest: None declared.
Similar articles
- A comparison between the effects of ginger, pyridoxine (vitamin B6) and placebo for the treatment of the first trimester nausea and vomiting of pregnancy (NVP).
Sharifzadeh F, Kashanian M, Koohpayehzadeh J, Rezaian F, Sheikhansari N, Eshraghi N. Sharifzadeh F, et al. J Matern Fetal Neonatal Med. 2018 Oct;31(19):2509-2514. doi: 10.1080/14767058.2017.1344965. Epub 2017 Jul 7. J Matern Fetal Neonatal Med. 2018. PMID: 28629250 Clinical Trial. - A randomized comparison of ginger and vitamin B6 in the treatment of nausea and vomiting of pregnancy.
Sripramote M, Lekhyananda N. Sripramote M, et al. J Med Assoc Thai. 2003 Sep;86(9):846-53. J Med Assoc Thai. 2003. PMID: 14649969 Clinical Trial. - Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis.
Hu Y, Amoah AN, Zhang H, Fu R, Qiu Y, Cao Y, Sun Y, Chen H, Liu Y, Lyu Q. Hu Y, et al. J Matern Fetal Neonatal Med. 2022 Jan;35(1):187-196. doi: 10.1080/14767058.2020.1712714. Epub 2020 Jan 14. J Matern Fetal Neonatal Med. 2022. PMID: 31937153 - Interventions for nausea and vomiting in early pregnancy.
Jewell D, Young G. Jewell D, et al. Cochrane Database Syst Rev. 2000;(2):CD000145. doi: 10.1002/14651858.CD000145. Cochrane Database Syst Rev. 2000. PMID: 10796155 Updated. Review. - Interventions for nausea and vomiting in early pregnancy.
Jewell D, Young G. Jewell D, et al. Cochrane Database Syst Rev. 2003;(4):CD000145. doi: 10.1002/14651858.CD000145. Cochrane Database Syst Rev. 2003. PMID: 14583914 Updated. Review.
Cited by
- The Use of Ginger Bioactive Compounds in Pregnancy: An Evidence Scan and Umbrella Review of Existing Meta-Analyses.
Tiani KA, Arenaz CM, Spill MK, Foster MJ, Davis JS, Bailey RL, Field MS, Stover PJ, MacFarlane AJ. Tiani KA, et al. Adv Nutr. 2024 Nov;15(11):100308. doi: 10.1016/j.advnut.2024.100308. Epub 2024 Sep 28. Adv Nutr. 2024. PMID: 39343171 Free PMC article. Review. - Ginger on Human Health: A Comprehensive Systematic Review of 109 Randomized Controlled Trials.
Anh NH, Kim SJ, Long NP, Min JE, Yoon YC, Lee EG, Kim M, Kim TJ, Yang YY, Son EY, Yoon SJ, Diem NC, Kim HM, Kwon SW. Anh NH, et al. Nutrients. 2020 Jan 6;12(1):157. doi: 10.3390/nu12010157. Nutrients. 2020. PMID: 31935866 Free PMC article. - Emerging Progress in Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum: Challenges and Opportunities.
Liu C, Zhao G, Qiao D, Wang L, He Y, Zhao M, Fan Y, Jiang E. Liu C, et al. Front Med (Lausanne). 2022 Jan 10;8:809270. doi: 10.3389/fmed.2021.809270. eCollection 2021. Front Med (Lausanne). 2022. PMID: 35083256 Free PMC article. Review. - Natural products for migraine: Data-mining analyses of Chinese Medicine classical literature.
Zhang CS, Lyu S, Zhang AL, Guo X, Sun J, Lu C, Luo X, Xue CC. Zhang CS, et al. Front Pharmacol. 2022 Oct 28;13:995559. doi: 10.3389/fphar.2022.995559. eCollection 2022. Front Pharmacol. 2022. PMID: 36386198 Free PMC article. - Pregnant women's attitudes towards complementary and alternative medicine and the use of phytotherapy during the COVID-19 pandemic: A cross-sectional study.
Durmaz A, Gun Kakasci C. Durmaz A, et al. PLoS One. 2024 Jan 2;19(1):e0296435. doi: 10.1371/journal.pone.0296435. eCollection 2024. PLoS One. 2024. PMID: 38165916 Free PMC article.
References
- Abolghasemi S, Razmjoo N. Effectiveness of ginger in nausea and vomiting during pregnancy. J Babol Univ Med Sci. 2004;6:17–20.
- Vutyavanich T, Kraisarin T, Ruangsri R. Ginger for nausea and vomiting in pregnancy: Randomized, double-masked, placebo-controlled trial. Obstet Gynecol. 2001;97:577–82. - PubMed
- Borrelli F, Capasso R, Aviello G, Pittler MH, Izzo AA. Effectiveness and safety of ginger in the treatment of pregnancy-induced nausea and vomiting. Obstet Gynecol. 2005;105:849–56. - PubMed
- Lacroix R, Eason E, Melzack R. Nausea and vomiting during pregnancy: A prospective study of its frequency, intensity, and patterns of change. Am J Obstet Gynecol. 2000;182:931–7. - PubMed
LinkOut - more resources
Full Text Sources
Other Literature Sources