Assessment of myocardial viability with SPECT and PET imaging - PubMed (original) (raw)
Review
. 1989 Sep;153(3):477-83.
doi: 10.2214/ajr.153.3.477.
Affiliations
- PMID: 2669461
- DOI: 10.2214/ajr.153.3.477
Review
Assessment of myocardial viability with SPECT and PET imaging
M D Cerqueira et al. AJR Am J Roentgenol. 1989 Sep.
Abstract
The use of thrombolytic therapy for the treatment of acute myocardial infarction has increased the number of patients presenting for assessment of myocardial viability. Stress SPECT 201Tl perfusion imaging performed in the conventional manner with delayed imaging at 4 hr can identify a large percentage of patients with ischemic but viable areas of myocardium. In some patients, delayed imaging up to as long as 24-48 hr after exercise may be required to show 201Tl redistribution indicative of viability. Thus, in most patients, stress 201Tl scintigraphy will correctly identify the presence of viable myocardium. PET imaging, with its ability to assess blood flow and metabolism separately, offers the ability to identify myocardial areas with diminished blood flow but preserved metabolism. Areas with such a blood flow-metabolism mismatch may benefit from revascularization, even in the absence of 201Tl redistribution. The exact role PET will play in the initial evaluation of patients presenting for assessment of myocardial viability remains to be established as more clinical data are accumulated.
Similar articles
- Myocardial perfusion imaging in the diagnosis of coronary artery disease.
Go RT, MacIntyre WJ, Cook SA, Neumann DR. Go RT, et al. Curr Opin Radiol. 1992 Aug;4(4):23-33. Curr Opin Radiol. 1992. PMID: 1627448 Review.
Cited by
- Review of Myocardial Ischemia, Scar, and Viability Estimation with Molecular Magnetic Resonance Imaging.
Sillanmäki S, Hartikainen S, Ylä-Herttuala E. Sillanmäki S, et al. Biomedicines. 2024 Jul 27;12(8):1681. doi: 10.3390/biomedicines12081681. Biomedicines. 2024. PMID: 39200146 Free PMC article. Review. - Calculation of Coronary Angiographic Total Blush in Patients with Coronary Artery Disease and its Prognostic Implication.
Gai JJ, Gai LY, Yan JJ, Jin QH. Gai JJ, et al. Chin Med J (Engl). 2015 Sep 20;128(18):2485-90. doi: 10.4103/0366-6999.164934. Chin Med J (Engl). 2015. PMID: 26365967 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources