PCNA appears in two populations of slow and fast diffusion with a constant ratio throughout S-phase in replicating mammalian cells - PubMed (original) (raw)

Oblique line scan illumination enables expansive, accurate and sensitive single-protein measurements in solution and in living cells.

Driouchi A, Bretan M, Davis BJ, Heckert A, Seeger M, Silva MB, Forrest WSR, Hsiung J, Tan J, Yang H, McSwiggen DT, Song L, Sule A, Abaie B, Chen H, Chhun B, Conroy B, Elliott LA, Gonzalez E, Ilkov F, Isaacs J, Labaria G, Lagana M, Larsen DD, Margolin B, Nguyen MK, Park E, Rine J, Tang Y, Vana M, Wilkey A, Zhang Z, Basham S, Ho JJ, Johnson S, Klammer AA, Lin K, Darzacq X, Betzig E, Berman RT, Anderson DJ. Driouchi A, et al. Nat Methods. 2025 Mar;22(3):559-568. doi: 10.1038/s41592-025-02594-6. Epub 2025 Feb 18. Nat Methods. 2025. PMID: 39966678 Free PMC article.